Evidence map›Paper›PMID 28329434›Full record

Trial reportJournal of traumatic stress2017

Integrated Treatment of PTSD and Substance Use Disorders: Examination of Imaginal Exposure Length.

Adam C Mills, Christal L Badour, Kristina J Korte, Therese K Killeen, Aisling V Henschel, Sudie E Back

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of traumatic stress, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01338506 (Integrated Treatment of Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Post-traumatic Stress Disorder and Substance Use Disorders), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01338506 nacompletednot on this map

Integrated Treatment of Operation Enduring Freedom/Operation Iraqi Freedom Veterans With Post-traumatic Stress Disorder and Substance Use Disorders

TypeinterventionalSponsorMedical University of South CarolinaRan2011 to 2016Enrolled81ConditionsPosttraumatic Stress Disorders, Combat Disorders, Alcohol Dependence, Drug DependenceArmsConcurrent Treatment with Prolonged Exposure (COPE)
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam C MillsDepartment of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.
Christal L BadourDepartment of Psychology, University of Kentucky, Lexington, Kentucky, USA.
Kristina J KorteDepartment of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.
Therese K KilleenDepartment of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.
Aisling V HenschelDepartment of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.
Sudie E BackDepartment of Psychiatry and Behavioral Sciences, Addictions Sciences Division, Medical University of South Carolina, Charleston, South Carolina, USA.

Funding

TRAINING IN ALCOHOL TREATMENT RESEARCHT32AA007474 · NIAAA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI John J. Woodward · 1987 to 2026
$8.5M
Integrated Treatment of OEF/OIF Veterans with PTSD and Substance Use DisordersR01DA030143 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2010 to 2014
$1.6M
Integrating Neurobiology and Neuroimaging into Research on Addiction and PTSDK02DA039229 · NIDA · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BACK, SUDIE E · 2015 to 2019
$779k
NIAAA NIH HHS T32 AA007474NIDA NIH HHS K02 DA039229NIDA NIH HHS R01 DA030143
6 · The paper itself

Abstract

Efforts to improve the efficiency of prolonged exposure (PE) therapy for posttraumatic stress disorder (PTSD) have demonstrated that reducing the length of imaginal exposures does not negatively affect treatment outcome. A recent adaptation of PE, called Concurrent Treatment of PTSD and Substance Use Disorders Using Prolonged Exposure [COPE], integrates substance use disorder treatment with PE in the same timeframe (twelve 90-minute sessions, 8 of which include imaginal exposure). The current study, which represents a subanalysis of a larger randomized controlled trial, examined how the length of imaginal exposures (nonrandomized and measured continually) related to PTSD, substance use, and depression in a sample of military veterans (N = 31) who completed the COPE treatment. Participants completed an average of 11.5 of the 12 therapy sessions and 7.2 of the 8 imaginal exposures during treatment. Results of 3 linear mixed models indicate that PTSD, substance use, and depressive symptoms all improved over the course of treatment (ps < .001; η

Indexed as

AdultDepressionFemaleHumansImplosive TherapyMaleMiddle AgedPsychiatric Status Rating ScalesSeverity of Illness IndexStress Disorders, Post-TraumaticSubstance-Related DisordersTime FactorsTreatment OutcomeVeterans

Identifiers

PMID28329434
PMCPMC5507581

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.