Evidence map›Paper›PMID 28329309›Full record

ArticleEuropean heart journal. Cardiovascular pharmacotherapy2017

Changes in oral anticoagulation for elective cardioversion: results from a European cardioversion registry.

Judit Papp, Endre Zima, Ramon Bover, Rasa Karaliute, Andrea Rossi, Catherine Szymanski, Rossella Troccoli, Jonas Schneider, Morten Wang Fagerland, A John Camm and 1 more

Erratum issuedOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in European heart journal. Cardiovascular pharmacotherapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Thromboembolic and bleeding complications after elective cardioversion of atrial fibrillation: a nationwide cohort study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  2. Review
  3. Cardioversion of atrial fibrillation and atrial flutter revisited: current evidence and practical guidance for a common procedure.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2020
    Article
  4. Review
  5. Review
  6. Rivaroxaban in atrial fibrillation cardioversion: an update.Therapeutics and clinical risk management · 2019
    Review
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 11 institutions in 8 countries.

Judit PappDepartment of Cardiology, Medical Center Hungarian Defence Forces, 44 Robert Karoly Krt., 1134 Budapest, Hungary.
Endre ZimaHeart and Vascular Center, Semmelweis University, 68 Varosmajor u., 1122 Budapest, Hungary.
Ramon BoverCardiology Department, University Hospital Clinico San Carlos, Profesor Martin Lagos s/n, 28040 Madrid, Spain.
Rasa KaraliuteLithuanian University of Health Sciences, Cardiology Clinic, 2 Eiveniu str., 50161 Kaunas, Lithuania.
Andrea RossiCardiothoracic Department, Tuscany Foundation Gabriele Monasterio, 1 Via G. Moruzzi, 56124 Pisa, Italy.
Catherine SzymanskiCardiology Department, Amiens University Hospital, Avenue Rene Laennec, 80000 Salouel Amiens, France.
Rossella TroccoliCardiologia Ospedaliera Polyclinic of Bari, 11 Piazza Giulio Cesare, 70124 Bari, Italy.
Jonas SchneiderBayer Healthcare, 178 Müllerstrasse, 13353 Berlin, Germany.
Morten Wang FagerlandOslo Centre for Biostatistics and Epidemiology, Research Support Services, Oslo University Hospital, Postboks 4950 Nydalen, 0424 Oslo, Norway.
A John CammMolecular and Clinical Research Institute and Cardiology Clinical Academic Group, St. George's University of London and Imperial College, London SW17 0RE, UK.
Dan AtarCardiology Department B and Faculty of Medicine, Oslo University Hospital, University of Oslo, 166 Kirkeveien, Building 3-A, 0407 Oslo, Norway.
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari · ITBayer (Germany) · DECentre Hospitalier Universitaire Amiens-Picardie · FRFondazione Toscana Gabriele Monasterio · ITHospital Clínico San Carlos · ESImperial College London · GBLithuanian University of Health Sciences · LTOslo University Hospital · NOSemmelweis University · HUUniversity of Oslo · NOZrínyi Miklós National Defence University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: In patients with atrial fibrillation (AF) pharmacological or electrical cardioversion may be performed to restore sinus rhythm. The procedure is associated with an increased risk of thromboembolic events, which can be significantly reduced by adequate anticoagulation (OAC). Our aim was to create a partly prospective, partly retrospective cardioversion registry, particularly focusing on OAC strategies in different European countries, and on emerging choice of OAC over time. Methods: From September 2014 to October 2015, cardioversions due to AF performed in six European city hospitals in five European countries (Hungary: Budapest-1 and -2; Italy: Bari and Pisa; France: Amiens; Spain: Madrid; and Lithuania: Kaunas) were recorded in the registry. Results: A total of 1101 patients (retrospective/prospective: 679/422, male/female: 742/359, mean age: 67.3 years ± 11.2) were registered. Most of the cardioversions were electrical (97%). Oral anticoagulants were administered in 87% of the patient, the usage of non-VKA oral anticoagulants (NOACs) vs Vitamin K antagonists (VKA) was 31.5% vs 68.5%, respectively. Seventy seven percent of the patients were given oral anticoagulants more than 3 weeks prior to the procedure, and 86% more than 4 weeks after the procedure. When using VKA, international normalized ratio (INR) at cardioversion was above 2.0 in 76% of the cases. A decline in VKA usage (P = 0.033) in elective cardioversion over approximately 1 year was observed. During the observation period, there was an increase in apixaban (P < 0.001), a slight increase in rivaroxaban (P = 0.028) and no changes in dabigatran (P = 0.34) usage for elective cardioversion. There were differences in use of OAC between the countries: Spain used most VKA (89%), while France used least VKA (39%, P < 0.001). Conclusion: According to current AF guidelines, NOACs are adequate alternatives to VKA for thromboembolic prevention in AF patients undergoing elective cardioversion. Our results indicate that NOAC use is increasing and there is a significant decrease in VKA use.

Indexed as

RegistriesAdministration, OralAgedAnticoagulantsAtrial FibrillationElectric CountershockEuropeFemaleFollow-Up StudiesHumansIncidenceMaleRetrospective StudiesThrombolytic TherapyTreatment OutcomeAnticoagulantsAnticoagulationAtrial fibrillationCardioversionNOACsRegistry

Identifiers

PMID28329309
PMCPMC5843131
OpenAlexW2595184800

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.