ArticlePloS one2017
Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- The wing melanization with 20-hydroxyecdysone modulation in Idea leuconoe clara (Lepidoptera: Nymphalidae).Journal of insect science (Online) · 2025Article
- Review of the effects of two major plastic compounds in arthropods: a call for increased interdisciplinarity and further studies at the population level.Environmental science and pollution research international · 2025Review
- TheProceedings. Biological sciences · 2022Article
- Alternative splicing in seasonal plasticity and the potential for adaptation to environmental change.Nature communications · 2022Article
- Dissections of Larval, Pupal and Adult Butterfly Brains for Immunostaining and Molecular Analysis.Methods and protocols · 2021Article
- Seasonal plasticity in anti-predatory strategies: Matching of color and color preference for effective crypsis.Evolution letters · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that steroid hormones regulate sexual behavior in vertebrates via organizational and activational effects. However, whether the organizational/activational paradigm applies more broadly to the sexual behavior of other animals such as insects is not well established. Here we describe the hormonal regulation of a sexual behavior in the seasonally polyphenic butterfly Bicyclus anynana is consistent with the characteristics of an organizational effect. By measuring hormone titer levels, quantifying hormone receptor gene expression in the brain, and performing hormone manipulations, we demonstrate steroid hormone signaling early in pupal development has a latent effect on adult male sexual behavior in B. anynana. These findings suggest the organizational/activational paradigm may be more highly conserved across animal taxa than previously thought.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.