ReviewLab animal2017
Side effects of pain and analgesia in animal experimentation.
Review in Lab animal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it, 121 citations in OpenAlex.
- Analgesic drug efficacy in mouse postoperative pain: a systematic review and meta-analysis.Lab animal · 2026Pooled it
- Administration of meloxicam to improve the welfare of mice in research: a systematic review (2000 - 2020).Veterinary research communications · 2022Pooled it
- Perioperative pregabalin does not alter behavioural or diffuse noxious inhibitory control responses in 2 rat models of chronic pain.Pain reports · 2026Article
- GrimACE: automated, multimodal cage-side assessment of pain and well-being in mice.Lab animal · 2026Article
- Pharmacokinetics and Analgesic Efficacy of a Novel Extended-Release Buprenorphine Formulation in Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Light-induced analgesia provides a drug-free optical method for pain relief via activation of TRAAK kNature communications · 2026Article
- Comparative Evaluation of Analgesics in a Murine Bile Duct Ligation Model.Biomedicines · 2025Article
- Pharmacokinetics of a Transdermal Buprenorphine Topical Solution in the Cynomolgus Macaque (Macaca fascicularis).Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Article
- A machine learning tool with light-based image analysis for automatic classification of 3D pain behaviors.Cell reports methods · 2025Article
- Impact of different anesthetic protocols during anesthesia for the establishment of a porcine model of acute kidney injury.Animal models and experimental medicine · 2025Article
- Current practices of pain assessment and analgesic use in laboratory mice: A 2022 FELASA Working Group survey.Laboratory animals · 2025Article
- Favorable pharmacokinetic and tolerability profiles make carprofen an attractive analgesic for subcutaneous injection and oral self-administration in rats.Scientific reports · 2025Article
- Pharmacokinetic Characteristics of Tolfenamic Acid in Freshwater Crocodiles (Animals : an open access journal from MDPI · 2025Article
- Animal Models of Human Pathology: Revision, Relevance and Refinements.Biomedicines · 2024Article
- Pharmacokinetics of Injectable Meloxicam and Buprenorphine in the Naked Mole-Rat (Journal of the American Association for Laboratory Animal Science : JAALAS · 2024Article
- Antinociceptive and Cardiorespiratory Effects of a Single Dose of Dexmedetomidine in Laboratory Mice Subjected to Craniotomy under General Anaesthesia with Isoflurane and Carprofen or Meloxicam.Animals : an open access journal from MDPI · 2024Article
- Effect of dog-owner interaction on post-operative pain perception and stress of dogs and variability in their behavioural patterns.Animal welfare (South Mimms, England) · 2024Article
- Effects of isoflurane and xylazine on inducing cerebral ischemia by the model of middle cerebral artery occlusion in mice.Laboratory animal research · 2023Article
- A buprenorphine depot formulation provides effective sustained post-surgical analgesia for 72 h in mouse femoral fracture models.Scientific reports · 2023Article
- Nitro-benzylideneoxymorphone, a bifunctional mu and delta opioid receptor ligand with high mu opioid receptor efficacy.Frontiers in pharmacology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review highlights selected effects of untreated pain and of widely used analgesics such as opioids, non-steroid anti-inflammatory drugs and antipyretics, to illustrate the relevance of carefully planned, appropriate and controlled analgesia for greater reproducibility in animal experiments involving laboratory rodents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.