ArticleCritical care medicine2017
Quantifying the Mortality Impact of Do-Not-Resuscitate Orders in the ICU.
Article in Critical care medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Associations of Anemia With Outcomes in Patients With Spontaneous Intracerebral Hemorrhage: A Meta-Analysis.Frontiers in neurology · 2019Pooled it
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- Comparative Evaluation of Risk of Death in Mechanically Ventilated Patients With COVID-19 and Influenza: A Population-Based Cohort Study.Journal of clinical medicine research · 2025Article
- Incidence of and Risk Factors for Do-Not-Resuscitate Orders in Critically Ill Children: Insights From a Tertiary Care Center in Saudi Arabia.Critical care research and practice · 2025Article
- Racial disparities in end-of-life suffering within surgical intensive care units.Trauma surgery & acute care open · 2024Article
- Outcome Prediction in Critically-Ill Patients with Venous Thromboembolism and/or Cancer Using Machine Learning Algorithms: External Validation and Comparison with Scoring Systems.International journal of molecular sciences · 2022Article
- The Impact of Do-Not-Resuscitate Order in the Emergency Department on Respiratory Failure after ICU Admission.Healthcare (Basel, Switzerland) · 2022Article
- Early Do-Not-Resuscitate Orders and Outcome After Intracerebral Hemorrhage.Neurocritical care · 2021Article
- Real-time prediction of COVID-19 related mortality using electronic health records.Nature communications · 2021Article
- Differences in Characteristics, Hospital Care and Outcomes between Acute Critically Ill Emergency Department Patients with Early and Late Do-Not-Resuscitate Orders.International journal of environmental research and public health · 2021Observational
- Clinical Features and Outcomes of Patients with Dementia Compared to an Aging Cohort Hospitalized During the Initial New York City COVID-19 Wave.Journal of Alzheimer's disease : JAD · 2021Article
- The prevalence of perceptions of mismatch between treatment intensity and achievable goals of care in the intensive care unit: a cross-sectional study.Intensive care medicine · 2019Article
- Characteristics and Outcomes of Ethics Consultations on a Comprehensive Cancer Center's Gastrointestinal Medical Oncology Service.HEC forum : an interdisciplinary journal on hospitals' ethical and legal issues · 2018Article
- Accurate and interpretable intensive care risk adjustment for fused clinical data with generalized additive models.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2018Article
- Use of intensive care unit priority model in directing intensive care unit admission in Sudan: A prospective cross-sectional study.International journal of critical illness and injury scienceArticle
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Authors and funding
10 authors at 4 institutions in 3 countries.
Funding
Abstract
objectivesWe quantified the 28-day mortality effect of preexisting do-not-resuscitate orders in ICUs.
designLongitudinal, retrospective study of patients admitted to five ICUs at a tertiary university medical center (Beth Israel Deaconess Medical Center, BIDMC, Boston, MA) between 2001 and 2008.
interventionNone. PATIENTS: Two cohorts were defined: patients with do not resuscitate advance directives on day 1 of ICU admission and a control group comprising patients with no limitations of level of care on ICU day 1 (full code). MEASUREMENTS AND MAIN
resultsThe primary outcome was mortality at 28 days after ICU admission. Of 19,007 ICU patients, 1,239 patients (6.5%) had a do-not-resuscitate order on the first day of ICU admission and survived 48 hours in the ICU. We matched those do-not-resuscitate patients with 2,402 patients with full-code status. Twenty-eight day and 1-year mortality were both significantly higher in the do-not-resuscitate group (33.9% vs 18.4% and 60.7% vs 40.2%; p < 0.001, respectively).
conclusionDo-not-resuscitate status is an independent risk factor for ICU mortality. This may reflect severity of illness not captured by other clinical factors, but the perceptions of the treating team related to do-not-resuscitate status could also be causally responsible for increased mortality in patients with do-not-resuscitate status.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.