ArticleThe American journal of bioethics : AJOB2017
Psychiatric Genomics and Mental Health Treatment: Setting the Ethical Agenda.
Article in The American journal of bioethics : AJOB, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Ethical and social issues in prediction of risk of severe mental illness: a scoping review and thematic analysis.BMC psychiatry · 2025Article
- Application of Genetic Testing for Anorexia Nervosa: An Ethical Analysis.Brain and behavior · 2025Article
- The promise of public health ethics for precision medicine: the case of newborn preventive genomic sequencing.Human genetics · 2022Review
- Ethical concerns relating to genetic risk scores for suicide.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2021Article
- In-vivo design feedback and perceived utility of a genetically-informed smoking risk tool among current smokers in the community.BMC medical genomics · 2021Article
- The role of causal knowledge in stigma considerations in African genomics research: Views of South African Xhosa people.Social science & medicine (1982) · 2021Article
- "It's all about delivery": researchers and health professionals' views on the moral challenges of accessing neurobiological information in the context of psychosis.BMC medical ethics · 2021Article
- Exploring how a genetic attribution to disease relates to stigma experiences of Xhosa patients with schizophrenia in South Africa.Social psychiatry and psychiatric epidemiology · 2020Article
- Reconceptualizing Psychosis: The Hearing Voices Movement and Social Approaches to Health.Health and human rights · 2020Article
- Psychosis, vulnerability, and the moral significance of biomedical innovation in psychiatry. Why ethicists should join efforts.Medicine, health care, and philosophy · 2020Article
- Psychiatric genomics researchers' perspectives on best practices for returning results to individual participants.Genetics in medicine : official journal of the American College of Medical Genetics · 2020Article
- Biomedical Explanations of Psychopathology and Their Implications for Attitudes and Beliefs About Mental Disorders.Annual review of clinical psychology · 2019Review
- Preventing discrimination based on psychiatric risk biomarkers.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2019Review
- Potential use of clinical polygenic risk scores in psychiatry - ethical implications and communicating high polygenic risk.Philosophy, ethics, and humanities in medicine : PEHM · 2019Review
- Predictive Psychiatric Genetic Testing in Minors: An Exploration of the Non-Medical Benefits.Journal of bioethical inquiry · 2018Article
- The Future Emerges from the Past : Comment on "Personal Genomic Testing, Genetic Inheritance, and Uncertainty".Journal of bioethical inquiry · 2017Article
- Beneficial and detrimental effects of genetic explanations for addiction.The International journal of social psychiatry · 2017Article
- Responsible Translation of Psychiatric Genetics and Other Neuroscience Developments: In Need of Empirical Bioethics Research.The American journal of bioethics : AJOB · 2017Article
- Psychiatric Genetics in a Risk Society.The American journal of bioethics : AJOB · 2017Article
- Psychiatric Genomics: Ethical Implications for Public Health in Lower- and Middle-Income Countries.The American journal of bioethics : AJOB · 2017Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Realizing the benefits of translating psychiatric genomics research into mental health care is not straightforward. The translation process gives rise to ethical challenges that are distinctive from challenges posed within psychiatric genomics research itself, or that form part of the delivery of clinical psychiatric genetics services. This article outlines and considers three distinct ethical concerns posed by the process of translating genomic research into frontline psychiatric practice and policy making. First, the genetic essentialism that is commonly associated with the genomics revolution in health care might inadvertently exacerbate stigma towards people with mental disorders. Secondly, the promises of genomic medicine advance a narrative of individual empowerment. This narrative could promote a fatalism towards patients' biology in ways that function in practice to undermine patients' agency and autonomy, or, alternatively, a heightened sense of subjective genetic responsibility could become embedded within mental health services that leads to psychosocial therapeutic approaches and the clinician-patient therapeutic alliance being undermined. Finally, adopting a genomics-focused approach to public mental health risks shifting attention away from the complex causal relationships between inequitable socio-economic, political, and cultural structures and negative mental health outcomes. The article concludes by outlining a number of potential pathways for future ethics research that emphasizes the importance of examining appropriate translation mechanisms, the complementarity between genetic and psychosocial models of mental disorder, the implications of genomic information for the clinician-patient relationship, and funding priorities and resource allocation decision making in mental health.
Indexed as
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.