ArticleJournal of clinical psychology2017
When Emotional Pain Becomes Physical: Adverse Childhood Experiences, Pain, and the Role of Mood and Anxiety Disorders.
Article in Journal of clinical psychology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
62 citing papers in PubMed, 5 syntheses or guidelines pooled it, 159 citations in OpenAlex.
- Pooled it
- Adverse childhood experience is associated with an increased risk of reporting chronic pain in adulthood: a stystematic review and meta-analysis.European journal of psychotraumatology · 2023Pooled it
- Co-Occurring Trauma and Non-Suicidal Self-Injury Among People With Chronic Pain: A Systematic Review.Current pain and headache reports · 2021Pooled it
- Emotional Dysregulation in Children and Adolescents With Psychiatric Disorders. A Narrative Review.Frontiers in psychiatry · 2021Pooled it
- Understanding the nature of psychiatric comorbidity in migraine: a systematic review focused on interactions and treatment implications.The journal of headache and pain · 2019Pooled it
- Anticipated Pain During Intrauterine Device Insertion.Journal of pediatric and adolescent gynecology · 2020Trial
- Screening for psychological trauma in patients with chronic pain: An Arizona survey of primary care providers identifies systems-level barriers to implementation.Psychological trauma : theory, research, practice and policy · 2026Article
- Alert to Hurt: Threat Appraisal Mediates the Association Between Attachment Anxiety and Perceptions of Pain Burden Among Healthy Young Adults.Behavioral sciences (Basel, Switzerland) · 2026Article
- Patient Perspectives on the Process and Outcome of Group Emotional Awareness and Expression Therapy for Chronic Pain.Journal of clinical psychology in medical settings · 2026Article
- Experience of Maltreatment Is Associated With Abdominal Pain Intensity and Health-Related Quality of Life in Children With Pain-Predominant Disorders of Gut-Brain Interaction.Neurogastroenterology and motility · 2026Article
- Association of Pain Intensity and Sensitivity with Childhood Trauma in Adolescents with Depressive Disorder: A Multicenter Study.Psychology research and behavior management · 2026Article
- More severe history of childhood adversity is linked to greater surface area of induced secondary hyperalgesia.medRxiv : the preprint server for health sciences · 2025Article
- Modifying the Adverse Childhood Experiences Questionnaire: Does a Continuous Approach Better Predict Life Course Outcomes?Journal of child & adolescent trauma · 2025Article
- Article
- Adverse Childhood Experiences and Health at Age 50 Years in the National Child Development Study.JAMA network open · 2025Article
- Adverse childhood experiences and multisite pain among adolescents in the United States.Pain reports · 2025Article
- "I Felt Like There Was Something Wrong in My Brain": Growing Up with Trauma - How Young People Conceptualise, Self-Manage and Seek Help for Mental Health Problems.Journal of child & adolescent trauma · 2025Article
- Impact of Early-Life Adversity on Cannabis Use: Exploring the Mediating and Moderating Effects of Chronic Pain.Cannabis and cannabinoid research · 2025Article
- Pain in alcohol use disorder: Evaluating effects of childhood trauma, perceived stress, and psychological comorbidity.Alcohol (Fayetteville, N.Y.) · 2024Article
- Beyond pain catastrophizing: rationale and recommendations for targeting trauma in the assessment and treatment of chronic pain.Expert review of neurotherapeutics · 2024Article
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveWe examined the association between retrospective reports of adverse childhood experiences (ACEs) and painful medical conditions. We also examined the mediating and moderating roles of mood and anxiety disorders in the ACEs-painful medical conditions relationship.
methodTen-year longitudinal data were obtained from the National Comorbidity Surveys (NCS-1, NCS-2; N = 5001). The NCS-1 obtained reports of ACEs, current health conditions, current pain severity, and mood and anxiety disorders. The NCS-2 assessed for painful medical conditions (e.g., arthritis/rheumatism, chronic back/neck problems, severe headaches, other chronic pain).
resultsSpecific ACEs (e.g., verbal and sexual abuse, parental psychopathology, and early parental loss) were associated with the painful medical conditions. Baseline measures of depression, bipolar disorder, and posttraumatic stress disorder were also associated with the number of painful medical conditions. Anxiety and mood disorders were found to partially mediate the ACEs-painful medical conditions relationship. We determined through mediation analyses that ACEs were linked to an increase in anxiety and mood disorders, which, in turn, were associated with an increase in the number of painful medical conditions. We determined through moderation analyses that ACEs had an effect on increasing the painful medical conditions at both high and low levels of anxiety and mood disorders; though, surprisingly, the effect was greater among participants at lower levels of mood and anxiety disorders.
conclusionThere are pernicious effects of ACEs across mental and physical domains. Dysregulation of the hypothalamic-pituitary-adrenal stress response and the theory of reserve capacity are reviewed to integrate our findings of the complex relationships.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.