ArticleJournal of biomedical optics2017
Evaluation of breast tissue with confocal strip-mosaicking microscopy: a test approach emulating pathology-like examination.
Article in Journal of biomedical optics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 30 citations in OpenAlex.
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- Vacuum-based specimen holder for rapid surgical specimen imaging.Biomedical optics express · 2025Article
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- Virtual Staining of Nonfixed Tissue Histology.Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc · 2024Review
- Piston-based specimen holder for rapid surgical and biopsy specimen imaging.Biomedical optics express · 2024Article
- Lesion detection in women breast's dynamic contrast-enhanced magnetic resonance imaging using deep learning.Scientific reports · 2023Article
- Fluorescence confocal microscopy for rapid evaluation of EUS fine-needle biopsy in pancreatic solid lesions.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2023Article
- Intraoperative imaging in pathology-assisted surgery.Nature biomedical engineering · 2022Review
- Slide Over: Advances in Slide-Free Optical Microscopy as Drivers of Diagnostic Pathology.The American journal of pathology · 2022Review
- Is Real-Time Microscopy on the Horizon? A Brief Review of the Potential Future Directions in Clinical Breast Tumor Microscopy Implementation.Virchows Archiv : an international journal of pathology · 2022Review
- High-speed mosaic imaging using scanner-synchronized stage position sampling.Journal of biomedical optics · 2022Article
- An international 3-center training and reading study to assess basal cell carcinoma surgical margins with ex vivo fluorescence confocal microscopy.Journal of cutaneous pathology · 2021Article
- Exploring the utility of Deep Red Anthraquinone 5 for digital staining of ex vivo confocal micrographs of optically sectioned skin.Journal of biophotonics · 2021Article
- Harnessing non-destructive 3D pathology.Nature biomedical engineering · 2021Review
- Comparison of Real-Time Fluorescence Confocal Digital Microscopy With Hematoxylin-Eosin-Stained Sections of Core-Needle Biopsy Specimens.JAMA network open · 2020Article
- Real-time Visualization of Breast Carcinoma in Pathology Specimens From Patients Receiving Fluorescent Tumor-Marking Agent Tozuleristide.Archives of pathology & laboratory medicine · 2019Article
- Ex Vivo Microscopy: A Promising Next-Generation Digital Microscopy Tool for Surgical Pathology Practice.Archives of pathology & laboratory medicine · 2019Review
- Rapid pathology of lumpectomy margins with open-top light-sheet (OTLS) microscopy.Biomedical optics express · 2019Article
- Clinical feasibility of optical coherence micro-elastography for imaging tumor margins in breast-conserving surgery.Biomedical optics express · 2018Article
- Rapid tissue histology using multichannel confocal fluorescence microscopy with focus tracking.Quantitative imaging in medicine and surgery · 2018Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
Confocal microscopy is an emerging technology for rapid imaging of freshly excised tissue without the need for frozen- or fixed-section processing. Initial studies have described imaging of breast tissue using fluorescence confocal microscopy with small regions of interest, typically 750 × 750 ?? ? m 2 . We present exploration with a microscope, termed confocal strip-mosaicking microscope (CSM microscope), which images an area of 2 × 2 ?? cm 2 of tissue with cellular-level resolution in 10 min of excision. Using the CSM microscope, we imaged 34 fresh, human, large breast tissue specimens from 18 patients, blindly analyzed by a board-certified pathologist and subsequently correlated with the corresponding standard fixed histopathology. Invasive tumors and benign tissue were clearly identified in CSM strip-mosaic images. Thirty specimens were concordant for image-to-histopathology correlation while four were discordant.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.