ArticleScientific reports2017
Bioactive silicon nitride: A new therapeutic material for osteoarthropathy.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 100 citations in OpenAlex.
- Silicon Nitride Coatings on Titanium for Cardiovascular Applications: Interface Engineering, Hemocompatibility, and Translational Challenges.Materials (Basel, Switzerland) · 2026Review
- Optimal cage biomaterials for fusion and subsidence outcomes in lumbar spinal fusion: a network meta-analysis of 4881 patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Review
- Advancements in biomaterials and bioactive solutions for lumbar spine fusion cages: Current trends and future perspectives.Bioactive materials · 2025Review
- Fabrication and Characterization of a Stretchable Sodium Alginate Hydrogel Patch Combined with Silicon Nitride and Metalized Halloysite Nanotubes to Develop a Chronic Wound Healing Treatment.International journal of molecular sciences · 2025Article
- Biomechanical Evaluation of Cervical Interbody Fusion Cages for Anterior Cervical Discectomy and Fusion With Variations in Morphology: A Finite Element Analysis.Biomedical engineering and computational biology · 2025Article
- Instantaneous Inactivation of Herpes Simplex Virus by Silicon Nitride Bioceramics.International journal of molecular sciences · 2023Article
- Bioactivation of 3D Cell-Imprinted Polydimethylsiloxane Surfaces by Bone Protein Nanocoating for Bone Tissue Engineering.ACS omega · 2022Article
- Silicon Nitride as a Biomedical Material: An Overview.International journal of molecular sciences · 2022Review
- Transforaminal lumbar interbody fusion with a silicon nitride cage demonstrates early radiographic fusion.Journal of spine surgery (Hong Kong) · 2022Article
- Mechanisms of instantaneous inactivation of SARS-CoV-2 by silicon nitride bioceramic.Materials today. Bio · 2021Article
- Silicon Nitride, a Bioceramic for Bone Tissue Engineering: A Reinforced Cryogel System With Antibiofilm and Osteogenic Effects.Frontiers in bioengineering and biotechnology · 2021Article
- In Vivo Regeneration of Large Bone Defects by Cross-Linked Porous Hydrogel: A Pilot Study in Mice Combining Micro Tomography, Histological Analyses, Raman Spectroscopy and Synchrotron Infrared Imaging.Materials (Basel, Switzerland) · 2020Article
- Promoting osteoblasts responsesJournal of orthopaedic translation · 2020Article
- Si-Fe-C-N Coatings for Biomedical Applications: A Combinatorial Approach.Materials (Basel, Switzerland) · 2020Article
- Clinical outcomes for lumbar fusion using silicon nitride versus other biomaterials.Journal of spine surgery (Hong Kong) · 2020Article
- Activity and Mechanism of Action of the Bioceramic Silicon Nitride as an Environmentally Friendly Alternative for the Control of the Grapevine Downy Mildew PathogenFrontiers in microbiology · 2020Article
- Clinical outcomes for anterior cervical discectomy and fusion with silicon nitride spine cages: a multicenter study.Journal of spine surgery (Hong Kong) · 2019Article
- The Effect of Coating Density on Functional Properties of SiNMaterials (Basel, Switzerland) · 2019Article
- Off-Stoichiometric Reactions at the Cell-Substrate Biomolecular Interface of Biomaterials:International journal of molecular sciences · 2019Article
- Bioglass functionalization of laser-patterned bioceramic surfaces and their enhanced bioactivity.Heliyon · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
While the reciprocity between bioceramics and living cells is complex, it is principally governed by the implant's surface chemistry. Consequently, a deeper understanding of the chemical interactions of bioceramics with living tissue could ultimately lead to new therapeutic strategies. However, the physical and chemical principles that govern these interactions remain unclear. The intricacies of this biological synergy are explored within this paper by examining the peculiar surface chemistry of a relatively new bioceramic, silicon nitride (Si
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.