Evidence map›Paper›PMID 28327645›Full record

ArticleScientific reports2017

A Novel Point-of-Care Smartphone Based System for Monitoring the Cardiac and Respiratory Systems.

Kwanghyun Sohn, Faisal M Merchant, Omid Sayadi, Dheeraj Puppala, Rajiv Doddamani, Ashish Sahani, Jagmeet P Singh, E Kevin Heist, Eric M Isselbacher, Antonis A Armoundas

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Emerging Wearable Acoustic Sensing Technologies.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  3. Utility of a Smartphone-Based System (cvrPhone) in Estimating Minute Ventilation from Electrocardiographic Signals.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2021
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Kwanghyun SohnCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Faisal M MerchantCardiology Division, Emory University School of Medicine, Atlanta, GA, USA.
Omid SayadiCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Dheeraj PuppalaCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Rajiv DoddamaniCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Ashish SahaniCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Jagmeet P SinghCardiology Division, Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
E Kevin HeistCardiology Division, Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, MA, USA.
Eric M IsselbacherHealthcare Transformation Lab, Massachusetts General Hospital, Boston, MA, USA.
Antonis A ArmoundasCardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
Massachusetts General Hospital · USEmory University · US

Funding

Harvard Clinical and Translational Science Center (UL1)UL1TR000170 · NCATS · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2012 to 2013
$31.4M
Prevention and Treatment of Ventricular TachyarrhythmiasR01HL135335 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ARMOUNDAS, ANTONIS A · 2017 to 2020
$2.1M
NCATS NIH HHS UL1 TR000170NHLBI NIH HHS R01 HL135335
6 · The paper itself

Abstract

Cardio-respiratory monitoring is one of the most demanding areas in the rapidly growing, mobile-device, based health care delivery. We developed a 12-lead smartphone-based electrocardiogram (ECG) acquisition and monitoring system (called "cvrPhone"), and an application to assess underlying ischemia, and estimate the respiration rate (RR) and tidal volume (TV) from analysis of electrocardiographic (ECG) signals only. During in-vivo swine studies (n = 6), 12-lead ECG signals were recorded at baseline and following coronary artery occlusion. Ischemic indices calculated from each lead showed statistically significant (p < 0.05) increase within 2 min of occlusion compared to baseline. Following myocardial infarction, spontaneous ventricular tachycardia episodes (n = 3) were preceded by significant (p < 0.05) increase of the ischemic index ~1-4 min prior to the onset of the tachy-arrhythmias. In order to assess the respiratory status during apnea, the mechanical ventilator was paused for up to 2 min during normal breathing. We observed that the RR and TV estimation algorithms detected apnea within 7.9 ± 1.1 sec and 5.5 ± 2.2 sec, respectively, while the estimated RR and TV values were 0 breaths/min and less than 100 ml, respectively. In conclusion, the cvrPhone can be used to detect myocardial ischemia and periods of respiratory apnea using a readily available mobile platform.

Indexed as

Point-of-Care SystemsSmartphoneAlgorithmsAnimalsElectrocardiographyHeartHeart Function TestsHumansMaleMonitoring, PhysiologicRespiratory Function TestsRespiratory SystemSwine

Identifiers

PMID28327645
PMCPMC5361153
OpenAlexW2599776613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.