Evidence map›Paper›PMID 28327521›Full record

ReviewMolecules (Basel, Switzerland)2017

Potential Antivirals: Natural Products Targeting Replication Enzymes of Dengue and Chikungunya Viruses.

Ana Flávia Costa da Silveira Oliveira, Róbson Ricardo Teixeira, André Silva de Oliveira, Ana Paula Martins de Souza, Milene Lopes da Silva, Sérgio Oliveira de Paula

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 71 citations in OpenAlex.

  1. Food science & nutrition · 2026
    Article
  2. Review
  3. Article
  4. Antiviral Potential ofInternational journal of molecular sciences · 2024
    Article
  5. Review
  6. Synthetic Derivatives of NaturalInternational journal of molecular sciences · 2024
    Article
  7. Review
  8. In silico and in vitro evaluation of silibinin: a promising anti-Chikungunya agent.In vitro cellular & developmental biology. Animal · 2022
    Article
  9. Review
  10. Review
  11. Article
  12. Flavonoids as Molecules With Anti-Frontiers in microbiology · 2021
    Review
  13. Review
  14. Review
  15. Review
  16. Antiviral potential of garlic (Trends in food science & technology · 2020
    Review
  17. Antiviral Natural Products for Arbovirus Infections.Molecules (Basel, Switzerland) · 2020
    Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ana Flávia Costa da Silveira OliveiraDepartamento de Biologia Geral, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. ana.oliveira@ifnmg.edu.br.
Róbson Ricardo TeixeiraDepartamento de Química, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. robsonr.teixeira@ufv.br.
André Silva de OliveiraDepartamento de Biologia Geral, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. andre.oliveira@ifnmg.edu.br.
Ana Paula Martins de SouzaDepartamento de Química, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. anapaulamartins20@hotmail.com.
Milene Lopes da SilvaDepartamento de Química, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. milenelopesdasilva@yahoo.com.br.
Sérgio Oliveira de PaulaDepartamento de Biologia Geral, Universidade Federal de Viçosa, Av. P.H. Rolfs, S/N, 36570-900 Viçosa, MG, Brazil. robsonr.teixeira@ufv.br.
Universidade Federal de Viçosa · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV) and chikungunya virus (CHIKV) are reemergent arboviruses that are transmitted by mosquitoes of the Aedes genus. During the last several decades, these viruses have been responsible for millions of cases of infection and thousands of deaths worldwide. Therefore, several investigations were conducted over the past few years to find antiviral compounds for the treatment of DENV and CHIKV infections. One attractive strategy is the screening of compounds that target enzymes involved in the replication of both DENV and CHIKV. In this review, we describe advances in the evaluation of natural products targeting the enzymes involved in the replication of these viruses.

Indexed as

Antiviral AgentsBiological ProductsChikungunya virusDengue VirusEnzyme InhibitorsMolecular StructurePlant ExtractsViral ProteinsVirus ReplicationAntiviral AgentsBiological ProductsEnzyme InhibitorsPlant ExtractsViral Proteinsantiviralchikungunyadenguenatural productsvirus enzymes

Identifiers

PMID28327521
PMCPMC6155337
OpenAlexW2600482145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.