ArticleAnnals of the American Thoracic Society2017
Indwelling Pleural Catheters for Patients with Hematologic Malignancies. A 14-Year, Single-Center Experience.
Article in Annals of the American Thoracic Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Incidence of complications from indwelling pleural catheter for pleural effusion: A meta-analysis.Clinical and translational science · 2023Pooled it
- Pleural effusion aetiology, presentation, treatment and outcome in haematological diseases: a review.Acta bio-medica : Atenei Parmensis · 2021Pooled it
- Causative pathogens and clinical outcomes of pleural infection in patients without and with indwelling pleural catheters - a retrospective study from a Danish pleural clinic.European clinical respiratory journal · 2026Article
- Pleural effusion in haematological malignancies: an educational position statement.Breathe (Sheffield, England) · 2026Review
- Intrathoracic manifestations of hematologic malignancies: a narrative review.Annals of translational medicine · 2025Review
- The Great Mimicker, a Rare Pleural Presentation.CHEST pulmonary · 2025Article
- Malignant Pleural Effusion: Palliative Managements and Indication for Pleurodesis Based on Survival Scores.Journal of surgical oncology · 2025Review
- Pleural Effusion: Shedding Light on Pleural Disease Beyond Infection and Malignancy.Medicina (Kaunas, Lithuania) · 2025Review
- Infective Pleural Effusions-A Comprehensive Narrative Review Article.Clinics and practice · 2024Review
- Indwelling tunneled pleural catheter infections and host related factors.Respiratory medicine · 2024Article
- Malignant pleural disease.Breathe (Sheffield, England) · 2023Review
- Treating Recurrent Pleural Disease: A Review of Indications and Technique for Chemical Pleurodesis for the Interventional Radiologist.Seminars in interventional radiology · 2022Review
- Diagnosis and Management of Malignant Pleural Effusion: A Decade in Review.Diagnostics (Basel, Switzerland) · 2022Review
- Article
- Indwelling pleural catheters for malignancy-associated pleural effusion: report on a single centre's ten years of experience.BMC pulmonary medicine · 2019Observational
- Recurrence of Gastric Mucosa-associated Lymphoid Tissue Lymphoma in the Pleura: A Case Report.Cureus · 2019Article
- Experiences in the treatment of refractory chylothorax associated with lymphoproliferative disorders.Orphanet journal of rare diseases · 2019Article
- Pleural effusions in hematologic malignancies and their management with indwelling pleural catheters.Current opinion in pulmonary medicine · 2018Review
- Indwelling pleural catheters: complications and management strategies.Journal of thoracic disease · 2018Review
- Predictors for spontaneous pleurodesis in patients with indwelling pleural catheters for malignant pleural effusion: a safety net hospital experience.Therapeutic advances in respiratory diseaseArticle
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
rationalePlacement of an indwelling pleural catheter is an established modality for symptom relief and pleurodesis in the treatment of malignant pleural effusion. Concerns remain regarding possible infectious complications, risk of hemorrhage, and the rate of pleurodesis with the use of pleural catheters in the treatment of hematologic malignancies.
objectivesThe goals of our study were: (1) to evaluate the safety and cumulative incidence of pleurodesis with indwelling pleural catheters for patients with hematologic malignancies, and (2) to evaluate overall survival of this cohort of patients with pleural effusions.
methodsWe performed a retrospective review of 172 patients with a hematologic malignancy who underwent placement of an indwelling pleural catheter between September 1997 and August 2011 at the University of Texas MD Anderson Cancer Center in Houston, Texas. A competing risk model analysis was used for complications and pleurodesis. Analysis was based on each patient's first intrapleural catheter.
resultsThere were 172 patients with lymphoma (58%), acute (16%) or chronic leukemia (16%), or multiple myeloma (10%). The effusions were characterized as malignant (85.5%), infectious (4.1%), volume overload (4.7%), or therapy-related (4.7%). Chylothorax was found in 20.1%. Pleural biopsies were obtained from 13 patients. The cumulative incidence of all complications was 13.6%, and the cumulative incidence of all significant catheter-related complications was 9.5%. The incidence of empyema was 2.9%, and major bleeding (requiring transfusion or intervention) was 1.7%. Thirty-day procedure-associated mortality was 0.6%. The cumulative incidence of pleurodesis at 180 days was 50%, with a median time to pleurodesis of 81 days for the entire cohort.
conclusionsIndwelling pleural catheters appear to be safe for patients with hematologic malignancies. Complications and the cumulative incidence of pleurodesis are comparable to those reported for patients with solid organ malignancies.
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