ArticleEnvironmental science & technology2017
Air Pollution and Climate Change Effects on Allergies in the Anthropocene: Abundance, Interaction, and Modification of Allergens and Adjuvants.
Article in Environmental science & technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 306 citations in OpenAlex.
- Short term physician visits and medication prescriptions for allergic disease associated with seasonal tree, grass, and weed pollen exposure across the United States.Environmental health : a global access science source · 2021Pooled it
- Interactive effects of allergens and air pollution on respiratory health: A systematic review.The Science of the total environment · 2021Pooled it
- Trial
- Climate Change and Food Allergy: Adaptations and Risks at the Intersection of Environment and Health.Comprehensive reviews in food science and food safety · 2026Review
- Differential Allergenicity and Heavy Metal Content in Dactylis glomerata and Lolium perenne Pollen Across Contrasting Environments.Environmental toxicology · 2026Article
- Allergic Respiratory Diseases in the Climate Change Context: Aerobiological Tools and Projections as Preventive Actions for Pollen-Induced Allergies.Medical sciences (Basel, Switzerland) · 2026Review
- Association of Short-Term Pollen Exposure With Lung Function in COPD Patients.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026Article
- Montelukast and Bilastine Combination Therapy in Allergic Rhinitis: A Narrative Review of Evidence.Cureus · 2026Review
- Unveiling microbial risks in Chinese household dust: a comprehensive analysis from absolute abundance to virulence unit.Microbiome · 2026Article
- Association between long-term PM2.5 exposure and risk of urticaria and allergic rhinitis in Korean children: a nationwide longitudinal cohort study.Epidemiology and health · 2026Article
- Article
- Influence of Atmospheric Pollutants on Allergic Sensitization to Cupressaceae,Life (Basel, Switzerland) · 2025Article
- Effects of meteorological factors and air pollution on the number of allergic rhinitis outpatient visits in Changchun city, China.Scientific reports · 2025Article
- Associations of environmental and community features with radiologic sinus inflammation in Pennsylvania, USA.Environmental epidemiology (Philadelphia, Pa.) · 2025Article
- Interactions among Cupressaceae pollen, air pollutants and meteorology in the urban and suburban areas of Beijing, China.Scientific reports · 2025Article
- Cockroach Microbiome Disrupts Indoor Environmental Microbial Ecology with Potential Public Health Implications.Environment & health (Washington, D.C.) · 2025Article
- Chinese Expert Consensus on the Impact of Ambient Air Pollution on Allergic Rhinitis and Recommendations for Mitigation Strategies.Allergy, asthma & immunology research · 2025Review
- ERS Congress 2024: highlights from the Epidemiology and Environment Assembly.ERJ open research · 2025Article
- Extracellular Vesicles Are Prevalent and Effective Carriers of Environmental Allergens in Indoor Dust.Environmental science & technology · 2025Article
- What is the relationship between exposure to environmental pollutants and severe mental disorders? A systematic review on shared biological pathways.Brain, behavior, & immunity - health · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
20 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Air pollution and climate change are potential drivers for the increasing burden of allergic diseases. The molecular mechanisms by which air pollutants and climate parameters may influence allergic diseases, however, are complex and elusive. This article provides an overview of physical, chemical and biological interactions between air pollution, climate change, allergens, adjuvants and the immune system, addressing how these interactions may promote the development of allergies. We reviewed and synthesized key findings from atmospheric, climate, and biomedical research. The current state of knowledge, open questions, and future research perspectives are outlined and discussed. The Anthropocene, as the present era of globally pervasive anthropogenic influence on planet Earth and, thus, on the human environment, is characterized by a strong increase of carbon dioxide, ozone, nitrogen oxides, and combustion- or traffic-related particulate matter in the atmosphere. These environmental factors can enhance the abundance and induce chemical modifications of allergens, increase oxidative stress in the human body, and skew the immune system toward allergic reactions. In particular, air pollutants can act as adjuvants and alter the immunogenicity of allergenic proteins, while climate change affects the atmospheric abundance and human exposure to bioaerosols and aeroallergens. To fully understand and effectively mitigate the adverse effects of air pollution and climate change on allergic diseases, several challenges remain to be resolved. Among these are the identification and quantification of immunochemical reaction pathways involving allergens and adjuvants under relevant environmental and physiological conditions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.