Evidence map›Paper›PMID 28326304›Full record

ReviewFrontiers in public health2017

HIV Diagnosis and Treatment through Advanced Technologies.

Hafiza Fizzah Zulfiqar, Aneeqa Javed, Sumbal, Bakht Afroze, Qurban Ali, Khadija Akbar, Tariq Nadeem, Muhammad Adeel Rana, Zaheer Ahmad Nazar, Idrees Ahmad Nasir and 1 more

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04165200 (Fecal Microbiota Transplantation as a Therapeutic Strategy for Patients Infected With HIV), which is not on this map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04165200 nacompletednot on this mapstarted 2018, after this paper: background citation

Fecal Microbiota Transplantation as a Therapeutic Strategy for Patients Infected With HIV

TypeinterventionalSponsorHospital Universitario Dr. Jose E. GonzalezRan2018 to 2020Enrolled22ConditionsHIV InfectionsArmsBlood and feces samples
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Novel Antiretroviral Therapeutic Strategies for HIV.Molecules (Basel, Switzerland) · 2021
    Review
  14. Review
  15. Nucleic acid testing and molecular characterization of HIV infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2019
    Review
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hafiza Fizzah ZulfiqarCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Aneeqa JavedCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
SumbalCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Bakht AfrozeCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Qurban AliCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Khadija AkbarCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Tariq NadeemCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Muhammad Adeel RanaDepartment of Microbiology, Quaid-i-Azam University , Islamabad , Pakistan.
Zaheer Ahmad NazarCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Idrees Ahmad NasirCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.
Tayyab HusnainCentre of Excellence in Molecular Biology, University of the Punjab , Lahore , Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human immunodeficiency virus (HIV) is the chief contributor to global burden of disease. In 2010, HIV was the fifth leading cause of disability-adjusted life years in people of all ages and leading cause for people aged 30-44 years. It is classified as a member of the family Retroviridae and genus Lentivirus based on the biological, morphological, and genetic properties. It infects different cells of the immune system, such as CD4+ T cells (T-helper cells), dendritic cells, and macrophages. HIV has two subtypes: HIV-1 and HIV-2. Among these strains, HIV-1 is the most virulent and pathogenic. Advanced diagnostic methods are exploring new ways of treatment and contributing in the reduction of HIV cases. The diagnostic techniques like PCR, rapid test, EIA, p24 antigen, and western blot have markedly upgraded the diagnosis of HIV. Antiretroviral therapy and vaccines are promising candidates in providing therapeutic and preventive regimes, respectively. Invention of CRISPR/Cas9 is a breakthrough in the field of HIV disease management.

Indexed as

antiretroviral therapyCRISPR/Cas9HIVlentivirusmacrophagesretoviridae

Identifiers

PMID28326304
PMCPMC5339269

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.