Evidence map›Paper›PMID 28326246›Full record

ArticleJournal of kidney cancer and VHL2014

Evaluation of steroid hormones and their receptors in development and progression of renal cell carcinoma.

Nigel C Bennett, Retnagowri Rajandram, Keng Lim Ng, Glenda C Gobe

Open access · diamondAbstract read
In one paragraph

Article in Journal of kidney cancer and VHL, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The influence of sex hormones on renal cell carcinoma.Therapeutic advances in medical oncology · 2024
    Review
  4. Article
  5. Article
  6. Article
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  12. Fine Particulate Matter Air Pollution and Mortality among Pediatric, Adolescent, and Young Adult Cancer Patients.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Nigel C BennettCentre for Kidney Disease Research, University of Queensland School of Medicine, Translational Research Institute, Woolloongabba, Brisbane, Australia; Oral Cancer Research Program, UQCCR, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia; Dept Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; University Malaya Cancer Research Institute (UMCRI), Kuala Lumpur, Malaysia.
Retnagowri RajandramCentre for Kidney Disease Research, University of Queensland School of Medicine, Translational Research Institute, Woolloongabba, Brisbane, Australia; Oral Cancer Research Program, UQCCR, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia; Dept Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; University Malaya Cancer Research Institute (UMCRI), Kuala Lumpur, Malaysia.
Keng Lim NgCentre for Kidney Disease Research, University of Queensland School of Medicine, Translational Research Institute, Woolloongabba, Brisbane, Australia; Oral Cancer Research Program, UQCCR, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia; Dept Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; University Malaya Cancer Research Institute (UMCRI), Kuala Lumpur, Malaysia.
Glenda C GobeCentre for Kidney Disease Research, University of Queensland School of Medicine, Translational Research Institute, Woolloongabba, Brisbane, Australia; Oral Cancer Research Program, UQCCR, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia; Dept Surgery, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia; University Malaya Cancer Research Institute (UMCRI), Kuala Lumpur, Malaysia.
University of Queensland · AUTranslational Research Institute · AUUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Steroid hormones and their receptors have important roles in normal kidney biology, and alterations in their expression and function help explain the differences in development of kidney diseases, such as nephrotic syndrome and chronic kidney disease. The distinct gender difference in incidence of renal cell carcinoma (RCC), with males having almost twice the incidence as females globally, also suggests a role for sex hormones or their receptors in RCC development and progression. There was a peak in interest in evaluating the roles of androgen and estrogen receptors in RCC pathogenesis in the late 20

Identifiers

PMID28326246
PMCPMC5345544
OpenAlexW2168589140

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.