ArticleInternational journal of nephrology2017
Childhood Nephrotic Syndrome Management and Outcome: A Single Center Retrospective Analysis.
Article in International journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed.
- Pediatric kidney transplant disparities.World journal of clinical pediatrics · 2026Article
- Racial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2023Article
- Determinants of medication adherence in childhood nephrotic syndrome and associations of adherence with clinical outcomes.Pediatric nephrology (Berlin, Germany) · 2022Observational
- Disease-Associated Systemic Complications in Childhood Nephrotic Syndrome: A Systematic Review.International journal of nephrology and renovascular disease · 2022Article
- Vascular Endothelial Growth Factor (VEGF) and Neopterin Levels in Children with Steroid-sensitive and Steroid-resistant Nephrotic Syndrome.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2021Article
- Article
- Text Messaging for Disease Monitoring in Childhood Nephrotic Syndrome.Kidney international reports · 2019Article
- Development of a novel mobile application to detect urine protein for nephrotic syndrome disease monitoring.BMC medical informatics and decision making · 2019Article
- Clinical course & management of childhood nephrotic syndrome in Germany: a large epidemiological ESPED study.BMC nephrology · 2019Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
There is a paucity of information on outpatient management and risk factors for hospitalization and complications in childhood nephrotic syndrome (NS). We described the management, patient adherence, and inpatient and outpatient usage of 87 pediatric NS patients diagnosed between 2006 and 2012 in the Atlanta Metropolitan Statistical Area. Multivariable analyses were performed to examine the associations between patient characteristics and disease outcome. We found that 51% of the patients were treated with two or more immunosuppressants. Approximately half of the patients were noted to be nonadherent to medications and urine protein monitoring. The majority (71%) of patients were hospitalized at least once, with a median rate of 0.5 hospitalizations per patient year. Mean hospital length of stay was 4.0 (3.8) days. Fourteen percent of patients experienced at least one serious disease complication. Black race, frequently relapsing/steroid-dependent and steroid-resistant disease, and the first year following diagnosis were associated with higher hospitalization rates. The presence of comorbidities was associated with longer hospital length of stay and increased risk of serious disease complications. Our results highlight the high morbidity and burden of NS and point to particular patient subgroups that may be at increased risk for poor outcome.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.