Evidence map›Paper›PMID 28326113›Full record

ArticlePsychiatry investigation2017

Factors that Affect the Adherence to ADHD Medications during a Treatment Continuation Period in Children and Adolescents: A Nationwide Retrospective Cohort Study Using Korean Health Insurance Data from 2007 to 2011.

Soo-Young Bhang, Young Sook Kwack, Yoo-Sook Joung, Soyoung Irene Lee, Bongseog Kim, Seok Han Sohn, Un-Sun Chung, Jaewon Yang, Minha Hong, Geon Ho Bahn and 4 more

Abstract read
In one paragraph

Article in Psychiatry investigation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Eliciting preferences for continuing medication among adult patients and parents of children with attention-deficit hyperactivity disorder.Health expectations : an international journal of public participation in health care and health policy · 2022
    Article
  6. Article
  7. Review
  8. Article
  9. Time to Stable Dose of Psychostimulants in Pediatric Patients With ADHD.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Soo-Young BhangDepartment of Psychiatry, Eulji University School of Medicine, Eulji University Eulji Hospital, Seoul, Republic of Korea.
Young Sook KwackDepartment of Psychiatry, Jeju National University College of Medicine, Jeju, Republic of Korea.
Yoo-Sook JoungDepartment of Psychiatry, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Soyoung Irene LeeDepartment of Psychiatry, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Republic of Korea.
Bongseog KimDepartment of Psychiatry, Sanggyepaik Hospital School of Medicine, Inje University, Seoul, Republic of Korea.
Seok Han SohnYonsei Clinic of Psychiatry, Seoul, Republic of Korea.
Un-Sun ChungDepartment of Psychiatry, Kyungpook National University School of Medicine, Daegu, Republic of Korea.
Jaewon YangStress Clinic, Korea Advanced Institute of Science and Technology (KAIST) Clinic, Daejeon, Republic of Korea.
Minha HongDepartment of Psychiatry, Myongji General Hospital, Goyang, Republic of Korea.
Geon Ho BahnDepartment of Psychiatry, Kyung Hee University School of Medicine, Seoul, Republic of Korea.
Hyung-Yun ChoiKorea Centers for Disease Control and Prevention, Cheongju, Republic of Korea.
In Hwan OhDepartment of Preventive Medicine, Kyung Hee University School of Medicine, Seoul, Republic of Korea.
Yeon Jung LeeDepartment of Psychiatry, Soonchunhyang University College of Medicine, Seoul Hospital, Seoul, Republic of Korea.
Jun-Won HwangDepartment of Psychiatry, Kangwon National University School of Medicine, Chuncheon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveSeveral factors, such as male gender, older age, type of insurance, comorbid conditions, and medication type, have been associated with attention-deficit/hyperactivity disorder (ADHD) medication adherence rates, but the results have been inconsistent. We analyzed data to answer several questions: 1) How old were patients who first refilled their treatment medications used primarily for ADHD, regardless of the medication type? 2) What socio-demographic factors are associated with medication adherence? 3) What medical conditions, such as medication type and comorbid diagnosis, influence adherence?

methodsWe analyzed National Health Insurance data, which comprised continuously enrolled Korean National Medical Insurance children (6-18 years) with at least 2 ADHD prescription claims (January 2008-December 2011). The persistence of use regarding the days of continuous therapy without a 30-day gap were measured continuously and dichotomously. Adherence, using a medication possession ratio (MPR), was measured dichotomously (80% cut-off).

resultsThe cumulative incidence of index cases that initiated medication refills for ADHD treatment during the 4 year period was 0.85%. The patients who exhibited a MPR greater than 80 comprised approximately 66%. The medication type, high school age groups, physician speciality, treatment at a private clinic, and comorbid conditions were associated with medication adherence during continuous treatment using a multivariate analysis.

conclusionA better understanding of ADHD treatment patterns may lead to initiatives targeted at the improvement of treatment adherence and persistence. Other factors, including the severity, family history, costs, type of comorbidities, and switching patterns, will be analyzed in future studies.

Indexed as

ADHDAdherenceAtomoxetineCohortComplianceStimulants

Identifiers

PMID28326113
PMCPMC5355013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.