ArticleFrontiers in microbiology2017
Temporal Variations in Cigarette Tobacco Bacterial Community Composition and Tobacco-Specific Nitrosamine Content Are Influenced by Brand and Storage Conditions.
Article in Frontiers in microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 60 citations in OpenAlex.
- Evaluating the Impact of Little Cigar Use on the Oral Bacterial Microbiota of Cigarette Smokers.Pathogens (Basel, Switzerland) · 2026Article
- Viable, Multi-Drug-Resistant Bacteria Recovered from E-Liquids Used with Commercial Electronic Cigarettes.International journal of environmental research and public health · 2025Article
- Unraveling the microbiome-aroma Nexus: a metagenomic and volatile compound analysis of Yunnan cigars.Frontiers in microbiology · 2025Article
- Bacterial community structure associated with smokeless tobacco reference products under different storage conditions and durations.Frontiers in public health · 2025Article
- Shaping the future of tobacco through microbial insights: a review of advances and applications.Frontiers in bioengineering and biotechnology · 2025Review
- Analytical Methodologies to Detect N-Nitrosamine Impurities in Active Pharmaceutical Ingredients, Drug Products and Other Matrices.Chemical research in toxicology · 2024Review
- Exploring the Microbial Diversity and Composition of Three Cigar Product Categories.Microbial ecology · 2024Article
- Microbial community and functions involved in smokeless tobacco product: a metagenomic approach.Applied microbiology and biotechnology · 2024Article
- Analyzing microbial community and volatile compound profiles in the fermentation of cigar tobacco leaves.Applied microbiology and biotechnology · 2024Article
- Article
- Effects of fermentation chamber temperature on microbes and quality of cigar wrapper tobacco leaves.Applied microbiology and biotechnology · 2023Article
- Study on the effect of enzymatic treatment of tobacco on HnB cigarettes and microbial succession during fermentation.Applied microbiology and biotechnology · 2023Article
- Tobacco microbial screening and application in improving the quality of tobacco in different physical states.Bioresources and bioprocessing · 2023Article
- Conventional tobacco products harbor unique and heterogenous microbiomes.Environmental research · 2023Article
- Study on the correlation between the dominant microflora and the main flavor substances in the fermentation process of cigar tobacco leaves.Frontiers in microbiology · 2023Article
- Variations in Bacterial Communities and Antibiotic Resistance Genes Across Diverse Recycled and Surface Water Irrigation Sources in the Mid-Atlantic and Southwest United States: A CONSERVE Two-Year Field Study.Environmental science & technology · 2022Article
- Composition and Ecological Functionality of Fungal Communities Associated with Smokeless Tobacco Products Mainly Consumed in India.Microbiology spectrum · 2022Article
- Comparative and analytical characterization of the oral bacteriome of smokeless tobacco users with oral squamous cell carcinoma.Applied microbiology and biotechnology · 2022Article
- Phyllosphere microbial community of cigar tobacco and its corresponding metabolites.Frontiers in microbiology · 2022Article
- Associations between microbial communities and key chemical constituents in U.S. domestic moist snuff.PloS one · 2022Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 1 country.
Funding
Abstract
Tobacco products, specifically cigarettes, are home to microbial ecosystems that may play an important role in the generation of carcinogenic tobacco-specific nitrosamines (TSNAs), as well as the onset of multiple adverse human health effects associated with the use of these products. Therefore, we conducted time-series experiments with five commercially available brands of cigarettes that were either commercially mentholated, custom-mentholated, user-mentholated, or non-mentholated. To mimic user storage conditions, the cigarettes were incubated for 14 days under three different temperatures and relative humidities (i.e., pocket, refrigerator, and room). Overall, 360 samples were collected over the course of 2 weeks and total DNA was extracted, PCR amplified for the V3V4 hypervariable region of the 16S rRNA gene and sequenced using Illumina MiSeq. A subset of samples (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.