Evidence map›Paper›PMID 28326033›Full record

ArticleFrontiers in aging neuroscience2017

Subcortical Shape Changes, Hippocampal Atrophy and Cortical Thinning in Future Alzheimer's Disease Patients.

Andrea M Kälin, Min T M Park, M Mallar Chakravarty, Jason P Lerch, Lars Michels, Clemens Schroeder, Sarah D Broicher, Spyros Kollias, Roger M Nitsch, Anton F Gietl and 3 more

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  17. Bone Marrow-Derived Mesenchymal Stem Cells andStem cells international · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrea M KälinInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Min T M ParkCerebral Imaging Centre, Douglas Mental Health University InstituteMontreal, QC, Canada; Schulich School of Medicine and Dentistry, Western UniversityLondon, ON, Canada.
M Mallar ChakravartyCerebral Imaging Centre, Douglas Mental Health University InstituteMontreal, QC, Canada; Departments of Psychiatry and Biological and Biomedical Engineering, McGill UniversityMontreal, QC, Canada.
Jason P LerchThe Hospital for Sick ChildrenToronto, ON, Canada; Department of Medical Biophysics, The University of TorontoToronto, ON, Canada.
Lars MichelsClinic of Neuroradiology, University Hospital Zurich, University of ZurichZurich, Switzerland; Center for MR Research, University Children's Hospital ZurichZurich, Switzerland.
Clemens SchroederInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Sarah D BroicherNeuropsychology Unit, Department of Neurology, University Hospital Zurich Zurich, Switzerland.
Spyros KolliasClinic of Neuroradiology, University Hospital Zurich, University of Zurich Zurich, Switzerland.
Roger M NitschInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Anton F GietlInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Paul G UnschuldInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Christoph HockInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.
Sandra E LehInstitute for Regenerative Medicine, University of Zurich Schlieren, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficacy of future treatments depends on biomarkers identifying patients with mild cognitive impairment at highest risk for transitioning to Alzheimer's disease. Here, we applied recently developed analysis techniques to investigate cross-sectional differences in subcortical shape and volume alterations in patients with stable mild cognitive impairment (MCI) (

Indexed as

Alzheimer's diseasecortical thicknesshippocampal subfieldsmild cognitive impairmentsubcortical shape analysis

Identifiers

PMID28326033
PMCPMC5339600

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.