Evidence map›Paper›PMID 28326013›Full record

ArticleFrontiers in molecular neuroscience2017

Molecular Chaperone Calnexin Regulates the Function of

Xi Xiao, Changyan Chen, Tian-Ming Yu, Jiayao Ou, Menglong Rui, Yuanfen Zhai, Yijing He, Lei Xue, Margaret S Ho

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.1field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 21 citations in OpenAlex.

  1. Lipid Metabolism in Relation to Calcium Homeostasis.Advances in experimental medicine and biology · 2026
    Review
  2. Piezo, Nephrocyte Function, and Slit Diaphragm Maintenance in Drosophila.Journal of the American Society of Nephrology : JASN · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
  9. Article
  10. Molecular characterization and distribution of the voltage-gated sodium channel, Para, in the brain of the grasshopper and vinegar fly.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2020
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Xi XiaoResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Changyan ChenShanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Institute of Intervention Vessel, Shanghai 10th People's Hospital, Tongji University Shanghai, China.
Tian-Ming YuResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Jiayao OuResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Menglong RuiKey Laboratory of Developmental Genes and Human Disease, Institute of Life Sciences, Southeast University Nanjing, China.
Yuanfen ZhaiResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Yijing HeResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Lei XueShanghai Key Laboratory of Signaling and Diseases Research, School of Life Science and Technology, Institute of Intervention Vessel, Shanghai 10th People's Hospital, Tongji University Shanghai, China.
Margaret S HoResearch Center for Translational Medicine, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Key Laboratory of Arrhythmias of the Ministry of Education of China, Shanghai East Hospital, Tongji University School of MedicineShanghai, China; Department of Anatomy and Neurobiology, Tongji University School of MedicineShanghai, China.
Tongji University · CNShanghai East Hospital · CNSoutheast University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuronal activity mediated by voltage-gated channels provides the basis for higher-order behavioral tasks that orchestrate life. Chaperone-mediated regulation, one of the major means to control protein quality and function, is an essential route for controlling channel activity. Here we present evidence that

Indexed as

Calnexin chaperonelocomotor behaviorNMJ synaptogenesisparalyticsodium channel

Identifiers

PMID28326013
PMCPMC5339336
OpenAlexW2593092078

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.