ArticleScientific reports2017
Night and day variations of sleep in patients with disorders of consciousness.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06323031 (Spontaneous Eye Blinking as a Diagnostic and Prognostic Marker in Patients With Disorders of Consciousness After Severe Acquired Brain Injury), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Spontaneous Eye Blinking as a Diagnostic and Prognostic Marker in Patients With Disorders of Consciousness After Severe Acquired Brain Injury
Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.
- Managing disorders of consciousness: the role of electroencephalography.Journal of neurology · 2021Pooled it
- Trial
- Detecting EEG index of arousal in sleeping patients with unresponsive wakefulness syndrome.iScience · 2026Article
- Non-invasive neuroregulation techniques applied to patients with consciousness disorders: a narrative review.Frontiers in human neuroscience · 2026Review
- Demographics-robust spontaneous eye blinking slowing in patients with severe acquired brain injury.Neuroscience of consciousness · 2026Article
- Do individuals with disorders of consciousness dream and mind wander? Implications for improving diagnosis and understanding patient wellbeing.Neuroscience of consciousness · 2025Article
- Analysis of the microstates of prolonged disorders of consciousness.Frontiers in neurology · 2025Article
- Article
- Exploring bispectral index as an alternative to polysomnography for long-term sleep monitoring in disorders of consciousness.Frontiers in neurology · 2024Article
- Twenty-four-hour rhythmicities in disorders of consciousness are associated with a favourable outcome.Communications biology · 2023Article
- Assessing consciousness in patients with disorders of consciousness using soft-clustering.Brain informatics · 2023Article
- Sleep in Disorders of Consciousness: A Brief Overview on a Still under Investigated Issue.Brain sciences · 2023Review
- Electroencephalogram-Based Brain Connectivity Analysis in Prolonged Disorders of Consciousness.Neural plasticity · 2023Article
- Assessing residual motor function in patients with disorders of consciousness by brain network properties of task-state EEG.Cognitive neurodynamics · 2022Article
- Does the Heart Fall Asleep?-Diurnal Variations in Heart Rate Variability in Patients with Disorders of Consciousness.Brain sciences · 2022Article
- Frontal and parietal lobes play crucial roles in understanding the disorder of consciousness: A perspective from electroencephalogram studies.Frontiers in neuroscience · 2022Review
- Sleep Treatments in Disorders of Consciousness: A Systematic Review.Diagnostics (Basel, Switzerland) · 2021Review
- A Systematic Review of Sleep in Patients with Disorders of Consciousness: From Diagnosis to Prognosis.Brain sciences · 2021Review
- Narrative Review: Quantitative EEG in Disorders of Consciousness.Brain sciences · 2021Review
- Consciousness and complexity: a consilience of evidence.Neuroscience of consciousness · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 1 country.
Funding
Abstract
Brain injuries substantially change the entire landscape of oscillatory dynamics and render detection of typical sleep patterns difficult. Yet, sleep is characterized not only by specific EEG waveforms, but also by its circadian organization. In the present study we investigated whether brain dynamics of patients with disorders of consciousness systematically change between day and night. We recorded ~24 h EEG at the bedside of 18 patients diagnosed to be vigilant but unaware (Unresponsive Wakefulness Syndrome) and 17 patients revealing signs of fluctuating consciousness (Minimally Conscious State). The day-to-night changes in (i) spectral power, (ii) sleep-specific oscillatory patterns and (iii) signal complexity were analyzed and compared to 26 healthy control subjects. Surprisingly, the prevalence of sleep spindles and slow waves did not systematically vary between day and night in patients, whereas day-night changes in EEG power spectra and signal complexity were revealed in minimally conscious but not unaware patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.