ArticleThe Journal of physiology1987
Adrenal cortical responses to vasoactive intestinal peptide in conscious hypophysectomized calves.
Article in The Journal of physiology, 1987. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 51 citations in OpenAlex.
- Sympathetic nervous system contributes to enhanced corticosterone levels following chronic stress.Psychoneuroendocrinology · 2016Article
- Nitric oxide plays a role in the regulation of adrenal blood flow and adrenocorticomedullary functions in the llama fetus.The Journal of physiology · 2002Article
- Effects of prevailing hypoxaemia, acidaemia or hypoglycaemia upon the cardiovascular, endocrine and metabolic responses to acute hypoxaemia in the ovine fetus.The Journal of physiology · 2002Article
- An in vivo nitric oxide clamp to investigate the influence of nitric oxide on continuous umbilical blood flow during acute hypoxaemia in the sheep fetus.The Journal of physiology · 2001Article
- Muscarinic involvement in vascular and adrenal medullary responses to splanchnic nerve stimulation in conscious calves.Experientia · 1994Article
- Autonomic control of adrenal function.Journal of anatomy · 1993Review
- Adrenal cortical and medullary responses to acetylcholine and vasoactive intestinal peptide in conscious calves.The Journal of physiology · 1993Article
- The role of corticotrophin releasing factor in relation to the neural control of adrenal function in conscious calves.The Journal of physiology · 1992Article
- Endocrine responses to intra-aortic infusions of acetylcholine in conscious calves.The Journal of physiology · 1991Article
- Adrenal responses to corticotrophin-releasing factor in conscious hypophysectomized calves.The Journal of physiology · 1990Article
- The effect of changes in adrenal blood flow on adrenal cortical responses to adrenocorticotrophin in conscious calves.The Journal of physiology · 1990Article
- Release of adrenocorticotrophin from the adrenal gland in the conscious calf.The Journal of physiology · 1990Article
- Adrenal responses to calcitonin gene-related peptide in conscious hypophysectomized calves.The Journal of physiology · 1989Article
- Secretion of corticotrophin releasing factor from the adrenal during splanchnic nerve stimulation in conscious calves.The Journal of physiology · 1988Article
- The adrenal contribution to the neuroendocrine responses to splanchnic nerve stimulation in conscious calves.The Journal of physiology · 1988Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
1. Right adrenal and various cardiovascular responses to an intra-aortic infusion of vasoactive intestinal polypeptide (VIP; 4 micrograms min-1 kg-1) have been investigated in the presence and absence of exogenous adrenocorticotrophin, (ACTH1-24; 5 ng min-1 kg-1, i.v.). The adrenal clamp technique was employed in conscious calves in which the pituitary stalk had been cauterized 3-4 days previously. 2. The i.v. infusion of ACTH1-24 increased mean plasma ACTH concentration by between 1000 and 1100 pg ml-1 and mean right cortisol output by about 700 ng min-1 kg-1. Under these conditions the intra-aortic infusion of VIP produced a further rise in mean adrenal cortisol output, together with a consequential rise in mean arterial plasma cortisol concentration, without affecting the concentration of ACTH in the arterial plasma significantly. In the absence of ACTH the same infusion of VIP had no detectable effect on adrenal cortisol output. 3. In each of the above respects this intra-aortic infusion of VIP closely mimicked the effect of stimulation of the peripheral end of the right splanchnic nerve in these animals, as it also did by causing a substantial fall in adrenal vascular resistance in the absence, but not in the presence, of ACTH. 4. It is concluded that release of this peptide from splanchnic nerve terminals in the adrenal gland most probably accounts, at least in part, for the powerful adrenocortical steroidogenic response to splanchnic nerve stimulation, that occurs in the presence of submaximal doses of ACTH.
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