Evidence map›Paper›PMID 28325902›Full record

ArticleScientific reports2017

Visit-to-visit Variability of Blood Pressure and Risk of Stroke: Results of the Kailuan Cohort Study.

Haijiang Dai, Yao Lu, Lu Song, Xiaohong Tang, Ying Li, Ruifang Chen, Aijing Luo, Hong Yuan, Shouling Wu

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Haijiang DaiCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China.
Yao LuCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China.
Lu SongGraduate School, North China University of Science and Technology, Tangshan, China.
Xiaohong TangDepartment of Cardiology, the Third Xiangya Hospital, Central South University, Changsha, China.
Ying LiCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China.
Ruifang ChenCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China.
Aijing LuoCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China.
Hong YuanCenter of Clinical Pharmacology, the Third Xiangya Hospital, Central South University, Changsha, China. yuanhong_xy3@163.com.
Shouling WuDepartment of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan, China. drwusl@163.com.
Central South University · CNThird Xiangya Hospital · CNNorth China University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uncertainty persists regarding the need to address blood pressure (BP) variability in the general population to reduce the heavy burden of stroke. In this cohort study, we prospectively recruited 57,927 participants from southeast of Beijing, who have completed all 3 health examinations between 2006 and 2010. BP variability was defined as the coefficient of variation (CV) across these 3 visits. Over a median follow-up of 3.0 years, we identified 582 first stroke cases. Of these, 489 (84.0%) were ischemic strokes and 94 (16.2%) were hemorrhagic strokes. After multivariable adjustment, the hazard ratios (HR) (95% Confidence Intervals, CI) of comparing participants in the highest versus lowest quartile of CV of systolic blood pressure (SBP) was 1.44 (1.11, 1.87) for any stroke, 1.33 (1.00, 1.77) for ischemic stroke, and 2.17 (1.09, 4.35) for hemorrhagic stroke. Similar results were also observed when the CV of SBP was considered as a continuous exposure variable (per SD increase). Moreover, higher variability of diastolic blood pressure (DBP) was also significantly associated with the risk of any stroke and specifically with hemorrhagic stroke, but not with ischemic stroke. In conclusion, higher visit-to-visit BP variability might be an important target to reduce stroke risk, particularly for hemorrhagic stroke.

Indexed as

Blood Pressure DeterminationChinaHypertensionHypotensionPrognosisProspective StudiesRisk AssessmentStroke

Identifiers

PMID28325902
PMCPMC5428298
OpenAlexW2679742137

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.