Evidence map›Paper›PMID 28325850›Full record

ArticleGenome research2017

Phenotypic diversity and genotypic flexibility of

Amy Huei-Yi Lee, Stephane Flibotte, Sunita Sinha, Adrianna Paiero, Rachel L Ehrlich, Sergey Balashov, Garth D Ehrlich, James E A Zlosnik, Joshua Chang Mell, Corey Nislow

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Strain-specific persistence ofJournal of medical microbiology · 2026
    Article
  4. Colony morphotype variation inJournal of bacteriology · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Genomic features, antimicrobial susceptibility, and epidemiological insights intoFrontiers in cellular and infection microbiology · 2023
    Article
  12. Review
  13. Adaptation and Evolution of Pathogens in the Cystic Fibrosis Lung.Journal of the Pediatric Infectious Diseases Society · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. One gene, multiple ecological strategies: A biofilm regulator is a capacitor for sustainable diversity.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  20. Panel 3: Genomics, precision medicine and targeted therapies.International journal of pediatric otorhinolaryngology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 3 countries.

Amy Huei-Yi LeeDepartment of Microbiology and Immunology.ORCID 0000-0003-3250-3246
Stephane FlibotteDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Sunita SinhaDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Adrianna PaieroDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Rachel L EhrlichDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA.
Sergey BalashovDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA.
Garth D EhrlichDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA.
James E A ZlosnikCentre for Preventing and Understanding Infection in Children, BC Children's Hospital, University of British Columbia, Vancouver, British Columbia V5Z 4H4, Canada.ORCID 0000-0002-9708-9034
Joshua Chang MellDepartment of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania 19102, USA.ORCID 0000-0003-0222-5636
Corey NislowDepartment of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.ORCID 0000-0002-4016-8874
University of British Columbia · CAInstitute for Molecular Medicine · US

Funding

MOLECULAR ANALYSIS OF PATHOGENS IN OTITIS MEDIA BY PCRR01DC002148 · NIDCD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI EHRLICH, GARTH D. · 1994 to 2017
$6.5M
NIDCD NIH HHS R01 DC002148
6 · The paper itself

Abstract

Chronic bacterial infections of the lung are the leading cause of morbidity and mortality in cystic fibrosis patients. Tracking bacterial evolution during chronic infections can provide insights into how host selection pressures-including immune responses and therapeutic interventions-shape bacterial genomes. We carried out genomic and phenotypic analyses of 215 serially collected

Indexed as

PhenotypePolymorphism, GeneticAdolescentAnimalsBiofilmsBurkholderia cenocepaciaBurkholderia InfectionsChildChild, PreschoolCystic FibrosisGenotypeHumansLungMothsVirulenceYoung Adult

Identifiers

PMID28325850
PMCPMC5378182
OpenAlexW2600844383

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.