Evidence map›Paper›PMID 28325799›Full record

ArticleDiabetes care2017

A Proposal for an Out-of-Range Glycemic Population Health Safety Measure for Older Adults With Diabetes.

Leonard Pogach, Chin-Lin Tseng, Orysya Soroka, Miriam Maney, David Aron

Abstract read
In one paragraph

Article in Diabetes care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leonard PogachVA New Jersey Health Care System, East Orange, NJ leonard.pogach@va.gov.
Chin-Lin TsengVA New Jersey Health Care System, East Orange, NJ.
Orysya SorokaVA New Jersey Health Care System, East Orange, NJ.
Miriam ManeyVA New Jersey Health Care System, East Orange, NJ.
David AronLouis Stokes Cleveland VA Medical Center, Cleveland, OH.

Funding

Evaluation of glycemic over and under-treatment indicators for high-risk VeteransI21HX001191 · VA · VA NEW JERSEY HEALTH CARE SYSTEM · PI POGACH, LEONARD MARSHALL · 2015 to 2015
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HSRD VA I21 HX001191
6 · The paper itself

Abstract

objectiveTo evaluate patient-level glycemic control and facility variation of a proposed out-of-range (OOR) measure (overtreatment [OT] [HbA RESEARCH DESIGN AND

methodsVeterans Health Administration patients ≥65 years of age in 2012 who were taking antihyperglycemic agents in 2013 were identified. Patient-level rates and facility-level rates/rankings were calculated by age and comorbid illness burden.

resultsWe identified 303,097 patients who were taking antiglycemic agents other than metformin only. The study population comprised 193,689 patients with at least one significant medical, neurological, or mental health condition; 98.2% were taking a sulfonylurea and/or insulin; 55.2% were aged 65-75 years; and 44.8% were aged >75 years. The 47.4% of patients 65-75 years met the OOR measure (33.4% OT, 14% UT), and 65.7% met the SM. For patients aged >75 years, rates were 48.1% for OOR (39.2% OT; 8.9% UT) and 73.2% for SM. Facility-level rates for OOR for patients aged 65-75 years ranged from 33.7 to 60.4% (median 47.4%), with a strong inverse correlation (ρ = -0.41) between SM and OOR performance rankings. Among the best-performing 20% facilities on the SM, 14 of 28 ranked in the worst-performing 20% on the OOR measure; 12 of 27 of the worst-performing 20% facilities on the SM ranked in the best-performing 20% on the OOR measure.

conclusionsFacility rankings that are based on an SM (potential benefits) and OOR measure (potential risks) differ substantially. An OOR for high-risk populations can focus quality improvement on individual patient evaluation to reduce the risk for short-term harms.

Indexed as

AgedBlood GlucoseComorbidityCreatinineDiabetes MellitusFemaleGlycated HemoglobinHumansHypoglycemic AgentsInsulinMaleMetforminRenal Insufficiency, ChronicRisk FactorsSulfonylurea CompoundsTreatment OutcomeBlood GlucoseCreatinineGlycated HemoglobinHypoglycemic AgentsInsulinMetforminSulfonylurea Compounds

Identifiers

PMID28325799
PMCPMC5360287

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.