Evidence map›Paper›PMID 28325761›Full record

ArticlemBio2017

The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis.

Norma V Solis, Marc Swidergall, Vincent M Bruno, Sarah L Gaffen, Scott G Filler

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 70 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Synergistic interactions betweenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. The role of the AHR in host-pathogen interactions.Nature reviews. Immunology · 2025
    Review
  8. Review
  9. Pathogenic strategies ofScience (New York, N.Y.) · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. bioRxiv : the preprint server for biology · 2023
    Article
  16. TheScience signaling · 2022
    Article
  17. Article
  18. Article
  19. Assessing Als3 Peptide-Binding Cavity and Amyloid-Forming Region Contributions toFrontiers in cellular and infection microbiology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Norma V SolisDivision of Infectious Diseases, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Marc SwidergallDivision of Infectious Diseases, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA.
Vincent M BrunoInstitute for Genome Sciences and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Sarah L GaffenDivision of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Scott G FillerDivision of Infectious Diseases, Department of Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California, USA sfiller@ucla.edu.
The Lundquist Institute · USHarbor–UCLA Medical Center · USUniversity of Maryland, Baltimore · USUniversity of Pittsburgh · US

Funding

UCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1M
Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, OWEN R · 2014 to 2023
$36.5M
C. albicans invasion and proliferation during oral infectionR01DE026600 · NIDCR · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI FILLER, SCOTT G, MITCHELL, AARON P · 2017 to 2021
$3.0M
IL-17 Receptor Signaling in the Oral MucosaR01DE022550 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GAFFEN, SARAH L · 2012 to 2016
$2.1M
NCATS NIH HHS UL1 TR001881NIAID NIH HHS U19 AI110820NIDCR NIH HHS R01 DE022550NIDCR NIH HHS R01 DE026600
6 · The paper itself

Abstract

Oropharyngeal candidiasis (OPC), caused predominantly by

Indexed as

EndocytosisAnimalsBasic Helix-Loop-Helix ProteinsCandidiasis, OralDisease Models, AnimalEpithelial CellsErbB ReceptorsMiceReceptors, Aryl HydrocarbonSignal Transductionsrc-Family KinasesAhr protein, mouseBasic Helix-Loop-Helix ProteinsEGFR protein, mouseErbB ReceptorsReceptors, Aryl Hydrocarbonsrc-Family Kinasesaryl hydrocarbon receptorCandida albicansepithelial cellshost cell invasioninterferon-gamma

Identifiers

PMID28325761
PMCPMC5362030
OpenAlexW2597915011

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.