ArticleJournal of psychiatric research2017
5-HTTLPR moderates the association between attention away from angry faces and prospective depression among youth.
Article in Journal of psychiatric research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- A Neurodevelopmental Model of Social Threat Sensitivity as a Mechanism Linking Fearful Temperament, Social Anxiety, and Depression in Youth.Journal of child and adolescent psychopharmacology · 2026Review
- Cognitive manipulation of emotional and non-emotional information in working memory of patients with depression: a rigid processing style.Frontiers in psychology · 2023Article
- Effects of SSRI Antidepressants on Attentional Bias toward Emotional Scenes in First-Episode Depressive Patients: Evidence from an Eye-Tracking Study.Psychiatry investigation · 2020Article
- Depression: A cognitive perspective.Clinical psychology review · 2019Review
- Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Attention bias to emotion has been studied as a risk factor associated with depression. No study has examined whether attention bias within the context of measured genetic risk leads to increased risk for clinical depressive episodes over time. The current study investigated whether genetic risk, as indexed by the serotonin-transporter-linked polymorphic region (5-HTTLPR), moderated the relationship between attention bias to emotional faces and clinical depression onset prospectively across 18-months in a community sample of youth (n = 428; mean age = 11.97, SD = 2.28; 59% girls). Youth who attended away from angry emotional faces and were homozygous for the S allele of the 5-HTTLPR polymorphism were at greater risk for prospective depressive episode onset. The current study's findings highlight the importance of examining risk for depression across multiple levels of analysis and demonstrate attention away from threat as a possible point of intervention related to attention bias modification and depression treatment among youth.
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Registered trials
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