Evidence map›Paper›PMID 28325617›Full record

ReviewCurrent opinion in neurobiology2017

Human genetics and sleep behavior.

Guangsen Shi, David Wu, Louis J Ptáček, Ying-Hui Fu

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. The SIK3-N783Y mutation is associated with the human natural short sleep trait.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Recent advances in sleep genetics.Current opinion in neurobiology · 2021
    Review
  9. Review
  10. Article
  11. Article
  12. A Rare Mutation of βNeuron · 2019
    Article
  13. Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Guangsen ShiKavli Institute for Fundamental Neuroscience, Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, United States; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA 94143, United States.
David WuKavli Institute for Fundamental Neuroscience, Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, United States.
Louis J PtáčekKavli Institute for Fundamental Neuroscience, Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, United States; Howard Hughes Medical Institute, University of California San Francisco, San Francisco, CA 94143, United States.
Ying-Hui FuKavli Institute for Fundamental Neuroscience, Weill Institute of Neuroscience, Department of Neurology, University of California San Francisco, San Francisco, CA 94143, United States. Electronic address: ying-hui.fu@ucsf.edu.
University of California, San Francisco · USHoward Hughes Medical Institute · US

Funding

GENETICS AND MOLECULAR CHARACTERIZATION OF ASPSR01HL059596 · NHLBI · UNIVERSITY OF UTAH · PI PTACEK, LOUIS J. · 1997 to 2012
$5.2M
Investigating Genetics of Human Natural Short SleepersR01NS072360 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2011 to 2015
$2.2M
A chemical genetic approach to dissect CKId & CKIe function in circadian rhythmR01GM079180 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FU, YING-HUI · 2008 to 2011
$1.3M
NHLBI NIH HHS R01 HL059596NIGMS NIH HHS R01 GM079180NINDS NIH HHS R01 NS072360
6 · The paper itself

Abstract

Why we sleep remains one of the greatest mysteries in science. In the past few years, great advances have been made to better understand this phenomenon. Human genetics has contributed significantly to this movement, as many features of sleep have been found to be heritable. Discoveries about these genetic variations that affect human sleep will aid us in understanding the underlying mechanism of sleep. Here we summarize recent discoveries about the genetic variations affecting the timing of sleep, duration of sleep and EEG patterns. To conclude, we also discuss some of the sleep-related neurological disorders such as Autism Spectrum Disorder (ASD) and Alzheimer's Disease (AD) and the potential challenges and future directions of human genetics in sleep research.

Indexed as

Genetic VariationElectroencephalographyGenetics, MedicalHumansNervous System DiseasesResearchSleepTime

Identifiers

PMID28325617
PMCPMC5511083
OpenAlexW2597356819

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.