ArticleBritish journal of cancer2017
Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma.
Article in British journal of cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Defining hypoxia in cancer: A landmark evaluation of hypoxia gene expression signatures.Cell genomics · 2025Article
- Clinical relevance and therapeutic predictive ability of hypoxia biomarkers in head and neck cancer tumour models.Molecular oncology · 2024Article
- Hypoxia-sensing CAR T cells provide safety and efficacy in treating solid tumors.Cell reports. Medicine · 2021Article
- Identification of a Hypoxia-Related Gene Signature for Predicting Systemic Metastasis in Prostate Cancer.Frontiers in cell and developmental biology · 2021Article
- A prognostic gene expression signature for oropharyngeal squamous cell carcinoma.EBioMedicine · 2020Article
- Inside the hypoxic tumour: reprogramming of the DDR and radioresistance.Cell death discovery · 2020Review
- Clinical update on head and neck cancer: molecular biology and ongoing challenges.Cell death & disease · 2019Review
- STIM1 overexpression in hypoxia microenvironment contributes to pancreatic carcinoma progression.Cancer biology & medicine · 2019Article
- Hypoxia gene expression signatures as predictive biomarkers for personalising radiotherapy.The British journal of radiology · 2019Review
- Mechanisms of resistance to anti-angiogenic treatments.Cancer drug resistance (Alhambra, Calif.) · 2019Review
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundHypoxia imaging is a promising tool for targeted therapy but the links between imaging features and underlying molecular characteristics of the tumour have not been investigated. The aim of this study was to compare hypoxia biomarkers and gene expression in oropharyngeal squamous cell carcinoma (OPSCC) diagnostic biopsies with hypoxia imaged with
methods
resultsHypoxic volume was significantly associated with a reported hypoxia gene signature (rho=0.57, P=0.045), but SUV
conclusions
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Registered trials
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