Evidence map›Paper›PMID 28324814›Full record

ArticleDrug and alcohol dependence2017

Risk of injury from alcohol, marijuana and other drug use among emergency department patients.

Cheryl J Cherpitel, Yu Ye, Gabriel Andreuccetti, Tim Stockwell, Kate Vallance, Clifton Chow, Jeffrey R Brubacher

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Cheryl J CherpitelAlcohol Research Group, Emeryville, CA 94608, Canada; Centre for Addictions Research of BC, University of Victoria, Victoria, BC, V8W 2Y2, Canada. Electronic address: ccherpitel@arg.org.
Yu YeAlcohol Research Group, Emeryville, CA 94608, Canada.
Gabriel AndreuccettiAlcohol Research Group, Emeryville, CA 94608, Canada.
Tim StockwellCentre for Addictions Research of BC, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Kate VallanceCentre for Addictions Research of BC, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Clifton ChowCentre for Addictions Research of BC, University of Victoria, Victoria, BC, V8W 2Y2, Canada.
Jeffrey R BrubacherDepartment of Emergency Medicine, University of British Columbia,Vancouver, BC, V6T 1Z4, Canada.
University of Victoria · CAAlcohol Research Group · USUniversity of British Columbia · CA

Funding

Cross-National Analysis of Alcohol & InjuryR01AA013750 · NIAAA · PUBLIC HEALTH INSTITUTE · PI CHERPITEL, CHERYL J · 2002 to 2018
$4.4M
CIHR MOP 123487NIAAA NIH HHS R01 AA013750
6 · The paper itself

Abstract

backgroundAlcohol is known to be associated with injury, but little is known of combined use of alcohol and other drugs on injury; especially important for marijuana, given increasing legalization of use in the U.S. and Canada.

methodsProbability samples of patients 18 and older were interviewed in the emergency department at two sites in Vancouver and one in Victoria, BC (n=1191 injured and 1613 non-injured patients). Case-control and case-crossover analyses were used to analyze risk of injury, based on self-reported alcohol and drug use (marijuana, stimulants, depressants) prior to injury.

resultsRisk of injury was significantly elevated (p<0.001) for alcohol use alone in both case-control (OR=2.72) and case-crossover analyses (OR=2.80) but not for any of the three drug classes. The interaction of alcohol with each class of drug was tested, and marginally significant only for marijuana in case-control analysis (OR=4.42; p=0.088). The interaction of alcohol and two or more drugs was also significant in case-control analysis (OR=03; p=0.035). The volume of alcohol consumed prior to injury was greater for those also using drugs during this time and positively associated with the number of drugs reported.

conclusionGiven the potential issues involved with both case-control and case-crossover study designs, the inconsistent findings suggest caution in reaching any definite conclusion regarding whether there is extra risk related to combined use of alcohol and marijuana, and is an important area for future research.

Indexed as

Emergency Service, HospitalAdolescentAdultAgedAlcohol DrinkingCanadaFemaleHumansMaleMarijuana SmokingMiddle AgedRiskSubstance-Related DisordersWounds and InjuriesYoung AdultAlcoholDrug useEmergency departmentInjury risk

Identifiers

PMID28324814
PMCPMC5400715
OpenAlexW2594882029

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.