Evidence map›Paper›PMID 28324619›Full record

ArticleClinical and experimental immunology2017

Identification of a HERV-K env surface peptide highly recognized in Rheumatoid Arthritis (RA) patients: a cross-sectional case-control study.

G Mameli, G L Erre, E Caggiu, S Mura, D Cossu, M Bo, M L Cadoni, A Piras, N Mundula, E Colombo and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
9.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Evolution ofInternational journal of molecular sciences · 2026
    Review
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  8. Review
  9. Human Endogenous Retroviruses Expression in Autoimmunity.The Yale journal of biology and medicine · 2024
    Review
  10. Article
  11. Microorganisms · 2024
    Review
  12. Article
  13. Article
  14. Autoimmunity: the neoantigen hypothesis.Frontiers in immunology · 2024
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

G MameliDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.
G L ErreDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
E CaggiuDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.
S MuraDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
D CossuDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.
M BoDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.
M L CadoniDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.
A PirasDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
N MundulaDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
E ColomboDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
G BuscettaDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
G PassiuDipartimento di Medicina Clinica e Sperimentale, Cattedra e Unità di Reumatologia, Università e AOU di Sassari, Sassari, Italy.
L A SechiDipartimento di Scienze Biomediche, Microbiologia Clinica e Sperimentale, Università degli Studi di Sassari, Sassari, Italy.ORCID 0000-0003-0566-2049
University of Sassari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous retroviruses (HERV) are believed to be pathogenic in several autoimmune diseases. Among them, HERV-K viruses have been reported recently to be involved in the pathogenesis of rheumatoid arthritis (RA). In this study we have explored the role of humoral immune response against HERV-K as a potential pathogenetic mechanism in RA. Four different peptides from the extracellular portion of the env protein of HERV-K (env-su

Indexed as

AdultAgedAntibodies, ViralArthritis, RheumatoidAutoantibodiesCase-Control StudiesCross-Sectional StudiesEndogenous RetrovirusesEnzyme-Linked Immunosorbent AssayFemaleHumansImmunity, HumoralImmunoglobulin GMaleMiddle AgedPeptidesAntibodies, ViralAutoantibodiesImmunoglobulin GPeptidesViral Envelope ProteinsHerv-Khumoral responsemolecular mimicrypeptidesrheumatoid arthritis

Identifiers

PMID28324619
PMCPMC5461087
OpenAlexW2605901947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.