Article3 Biotech2013
Alpinia: the gold mine of future therapeutics.
Article in 3 Biotech, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05170113 (A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among Overall Healthy Participants), which is not on this map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Pilot, Randomized, Double-blind, Placebo-controlled, Parallel Design Study to Evaluate the Effectiveness and Safety of an Alpinia Galanga Formulation, Theacrine Formulation, and Caffeine Formulation on Fatigue, Mental Acuity, and Cognitive Health Among Overall Healthy Participants
Who cites it
19 citing papers in PubMed, 93 citations in OpenAlex.
- Anti-Inflammatory Activities of Some Plants of GenusJournal of experimental pharmacology · 2025Review
- Antimicrobial Potential of Natural Compounds of Zingiberaceae Plants and their Synthetic Analogues: A Scoping Review ofCurrent topics in medicinal chemistry · 2024Article
- Lactating buffalos' productive performance, ruminal kinetics, nutrients digestibility and oxidative status as response to supplementing diets withAnimal biotechnology · 2023Article
- Phytogenics in Ginger,Animals : an open access journal from MDPI · 2023Review
- Evaluation of Antifungal Activity ofMedicines (Basel, Switzerland) · 2023Article
- Phytochemical analysis, antioxidant, antimicrobial, and anti-enzymatic properties ofFrontiers in plant science · 2023Article
- Exploration of Lamiaceae in Cardio Vascular Diseases and Functional Foods: Medicine as Food and Food as Medicine.Frontiers in pharmacology · 2022Review
- Investigation of acute effects of topical Alpinia officinarum (galangal) treatment in experimental contact type burns and comparison with topical silver sulfadiazine treatment.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Therapeutic Promises of Medicinal Plants in Bangladesh and Their Bioactive Compounds against Ulcers and Inflammatory Diseases.Plants (Basel, Switzerland) · 2021Review
- Emerging roles of cardamonin, a multitargeted nutraceutical in the prevention and treatment of chronic diseases.Current research in pharmacology and drug discovery · 2021Review
- Anti-cancer properties of specific Chinese herbal medicines for hepatocellular carcinoma treatment.European journal of integrative medicine · 2020Review
- Using ICPC-2 Standard to Identify Thai Zingiberaceae of Pharmacological Interest.Plants (Basel, Switzerland) · 2020Article
- Topical Anti-Inflammatory Activity of Essential Oils ofEvidence-based complementary and alternative medicine : eCAM · 2020Article
- Herbal management of hepatocellular carcinoma through cutting the pathways of the common risk factors.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018Review
- Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) for Human Longevity in Okinawa, Japan?Nutrients · 2018Review
- Nature's Electric Potential: A Systematic Review of the Role of Bioelectricity in Wound Healing and Regenerative Processes in Animals, Humans, and Plants.Frontiers in physiology · 2017Review
- Dihydro-5,6-dehydrokavain (DDK) from Alpinia zerumbet: Its Isolation, Synthesis, and Characterization.Molecules (Basel, Switzerland) · 2015Review
- Antioxidant potential, cytotoxic activity and total phenolic content of Alpinia pahangensis rhizomes.BMC complementary and alternative medicine · 2013Article
- A Review on the Pharmacological Activities and Phytochemicals ofPharmacognosy reviewsReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since prehistoric era, plant-derived drugs were much preferred due to their less side effects than drugs of synthetic origin. Bioassay-guided selection of active fraction of a plant extract and further isolation and characterization of the pure bioactive compounds are in practice in both academic and industrial research. Zingiberaceae, a medicinally important, ornamental, monocotyledonous family has potential members in the tribe Alpinieae, among which the genus Alpinia is studied under this current review due to its wide range of biomedical applications. The members in the genus possess many bioactive compounds against harmful microbes to deadly diseases like cancer by regulating the different signalling pathway systems. Several compounds have been discovered and found to deliver diversified biological efficacy either in vitro or in vivo against a range of diseases. The chemical profiling of the genus and investigation of crude essential oils and individual bioactive compounds towards the therapeutic importance in various disciplines have been documented in the current review.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.