Evidence map›Paper›PMID 28324271›Full record

ArticleJournal of assisted reproduction and genetics2017

Anti-Mullerian hormone concentrations in individual follicular fluids within one stimulated IVF cycle resemble blood serum values.

Michael Schenk, Julia Maria Kröpfl, Barbara Obermayer-Pietsch, Elisabeth Feldmeier, Gregor Weiss

Open access · hybridAbstract read
In one paragraph

Article in Journal of assisted reproduction and genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The role of anti-Müllerian hormone (AMH) in ovarian disease and infertility.Journal of assisted reproduction and genetics · 2020
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Michael SchenkDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, 8143, Dobl, Austria.
Julia Maria KröpflExercise Physiology Lab, Institute of Human Movement Sciences and Sport, ETH Zürich, Winterthurerstrasse 190, 8057, Zürich, Switzerland.
Barbara Obermayer-PietschDivision of Endocrinology and Diabetology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036, Graz, Austria.
Elisabeth FeldmeierDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, 8143, Dobl, Austria.
Gregor WeissDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, 8143, Dobl, Austria. gregor.weiss@kinderwunsch-institut.at.ORCID http://orcid.org/0000-0003-1045-8595
ETH Zurich · CHMedical University of Graz · ATWunschbaby Institut für Kinderwunsch · AT

Funding

Austrian Research Promotion Agency 856169
6 · The paper itself

Abstract

purposeAnti-Mullerian hormone (AMH) is commonly known as the most potent marker for ovarian reserve due to its decline as female age increases. While serum AMH (sAMH) levels have been intensively investigated, there is less data regarding AMH concentrations in follicular fluid (FF), since FF has usually been designated as waste product during oocyte collection in assisted reproductive technologies. This pilot study investigated follicle AMH concentrations (fAMH) of several follicles per ovary, individually collected with the Steiner-Tan needle, and compared them to sAMH concentrations in women undergoing IVF treatment. We hypothesized that there is no difference of fAMH concentrations in individual follicles and that these concentrations resemble the sAMH value of the patient.

methodsPatients were stimulated with a gonadotropin-releasing hormone antagonist ovarian hyperstimulation protocol. On the day of oocyte retrieval, serum samples and FF from all individual follicles from one stimulated IVF cycle were collected and individually analyzed for AMH concentrations.

resultsIntracyclic mean fAMH values (n

conclusionsIn conclusion, our results clearly showed that individual fAMH concentrations reflected sAMH values and that fAMH concentrations did not significantly differ within one patient. In future studies, it will be interesting to correlate individual fAMH values to the respective embryo development and overall pregnancy outcome in order to improve IVF treatments and to refrain from embryo overproduction.

Indexed as

Fertilization in VitroReproductive Techniques, AssistedAdultAnti-Mullerian HormoneEmbryo ImplantationFemaleFollicular FluidHumansOocyte RetrievalOvarian ReservePregnancyPregnancy RateProgesteroneAnti-Mullerian HormoneProgesteroneAnti-Mullerian hormoneFollicular fluidIVFSteiner-Tan needle

Identifiers

PMID28324271
PMCPMC5581778
OpenAlexW2598344995

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.