ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2017
New classification for the treatment of pyogenic spondylodiscitis: validation study on a population of 250 patients with a follow-up of 2 years.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.
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Who cites it
78 citing papers in PubMed, 143 citations in OpenAlex.
- Epidural Abscess in Routine Preoperative MRI Reports Versus Documented Operative Findings, and Exploratory Mortality Risk Factors in Surgically Treated Spondylodiscitis: A Retrospective Single-Centre Study.Journal of clinical medicine · 2026Article
- Recommendations of the International Consensus Meeting (ICM) 2025 on Spinal Infections: Part A Pyogenic Spondylodiscitis.Global spine journal · 2026Article
- Decompressive Laminectomy for Neurological Complications of Spondylodiscitis: A Case Series of 15 Patients.Journal of personalized medicine · 2026Article
- When infection becomes architecture: structural predictors of surgical management in spondylodiscitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Article
- Article
- Impact of abscess type on outcomes following posterior fixation for thoracolumbar pyogenic spondylitis: a multicenter retrospective cohort study.Asian spine journal · 2026Article
- Whole-Spine MRI Reveals High Prevalence of Multifocal Spondylodiscitis and Identifies a High-Risk Subgroup: A Retrospective Cohort Study of 274 Patients.Medicina (Kaunas, Lithuania) · 2026Article
- MRI spondylodiscitis severity index: A novel scoring system based on contrast-enhanced MRI of the spine for predicting the clinical course and severity of pyogenic spondylodiscitis.Skeletal radiology · 2026Article
- Application of a multidimensional and process-oriented evaluation system in PELD bridging therapy for lumbar spinal infections: a self-controlled retrospective study of 27 cases.Frontiers in cellular and infection microbiology · 2026Article
- Spinal infections.Frontiers in neuroscience · 2026Review
- Changing Tides in the Treatment of Spondylodiscitis? A Retrospective, Monocentric Comparison of Mortality and Quality of Life After Surgical and Conservative Treatment.Clinics and practice · 2025Article
- Challenges and limitations of the existing scoring systems for postoperative outcomes in thoracolumbar pyogenic spondylitis: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Disc penetration sign: an distinctive MRI feature as a predictor of surgical necessity in pyogenic spondylitis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Early and late mortality in vertebral osteomyelitis: who dies within the first year after diagnosis.Infection · 2025Article
- Local antibiotic carriers in the surgical management of pyogenic spondylodiscitis : First comparative evaluation of gentamicin-loaded versus vancomycin-loaded efficacy.Orthopadie (Heidelberg, Germany) · 2025Article
- What Is Worse: A Comparison of Solitary Versus Multifocal Pyogenic Spondylodiscitis Using a Nationwide Analysis of Readmission Rates and Risk Factors.Journal of clinical medicine · 2025Article
- Surgical treatment of unstable spondylodiscitis with posterior instrumentation and bioactive glass (BAG-S53P4): surgical technique and results at medium-term follow-up.Journal of spine surgery (Hong Kong) · 2025Article
- Review
- Uniportal endoscopic decompression and debridement for infectious diseases of spine with neurological deficits: a retrospective study in China.Asian spine journal · 2025Article
- [Medecine tropicale et sante internationale · 2025Article
18 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePyogenic spondylodiscitis (PS) is still burdened by a high rate of orthopedic and neurological complications. Despite the rising incidence, the choice of a proper orthopedic treatment is often delayed by the lack of clinical data. The aim of this study was to propose a clinical-radiological classification of pyogenic spondylodiscitis to define a standard treatment algorithm.
methodsBased on data from 250 patients treated from 2008 to 2015, a clinical-radiological classification of pyogenic spondylodiscitis was developed. According to primary classification criteria (bone destruction or segmental instability, epidural abscesses and neurological impairment), three main classes were identified. Subclasses were defined according to secondary criteria. PS without segmental instability or neurological impairment was treated conservatively. When significant bone loss or neurological impairment occurred, surgical stabilization and/or decompression were performed. All patients underwent clinical and radiological 2-year follow-up.
resultsType A PS occurred in 84 patients, while 46 cases were classified as type B and 120 as type C. Average time of hospitalization was 51.94 days and overall healing rate was 92.80%. 140 patients (56.00%) were treated conservatively with average time of immobilization of 218.17 ± 9.89 days. Both VAS and SF-12 scores improved across time points in all classes. Residual chronic back pain occurred in 27 patients (10.80%). Overall observed mortality was 4.80%.
conclusionsStandardized treatment of PS is highly recommended to ensure patients a good quality of life. The proposed scheme includes all available orthopedic treatments and helps spine surgeons to significantly reduce complications and costs and to avoid overtreatment.
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