Evidence map›Paper›PMID 28323670›Full record

ReviewCurrent opinion in anaesthesiology2017

Prevention of respiratory complications of the surgical patient: actionable plan for continued process improvement.

Katarina J Ruscic, Stephanie D Grabitz, Maíra I Rudolph, Matthias Eikermann

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Current opinion in anaesthesiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03198208 (Effects of Intraoperative Fentanyl Dose on Postoperative Respiratory Complications), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03198208 unknown statusnot on this map

Effects of Intraoperative Fentanyl Dose on Postoperative Respiratory Complications

Typeobservational_patient_registrySponsorMassachusetts General HospitalRan2007 to 2018Enrolled183,396ConditionsFentanyl, Opioid Use, Surgery, Respiratory ComplicationArmsFentanyl dose administration
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Katarina J RuscicaDepartment of Anesthesia, Critical Care, and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA bKlinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Essen, Germany.
Stephanie D Grabitz
Maíra I Rudolph
Matthias Eikermann
Harvard University · USMassachusetts General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewPostoperative respiratory complications (PRCs) increase hospitalization time, 30-day mortality and costs by up to $35 000. These outcomes measures have gained prominence as bundled payments have become more common. RECENT

findingsResults of recent quantitative effectiveness studies and clinical trials provide a framework that helps develop center-specific treatment guidelines, tailored to minimize the risk of PRCs. The implementation of those protocols should be guided by a local, respected, and visible facilitator who leads proper implementation while inviting center-specific input from surgeons, anesthesiologists, and other perioperative stakeholders. SUMMARY: Preoperatively, patients should be risk-stratified for PRCs to individualize intraoperative choices and postoperative pathways. Laparoscopic compared with open surgery improves respiratory outcomes. High-risk patients should be treated by experienced providers based on locally developed bundle-interventions to optimize intraoperative treatment and ICU bed utilization. Intraoperatively, lung-protective ventilation (procedure-specific positive end-expiratory pressure utilization, and low driving pressure) and moderately restrictive fluid therapy should be used. To achieve surgical relaxation, high-dose neuromuscular blocking agents (and reversal agents) as well as high-dose opioids should be avoided; inhaled anesthetics improve surgical conditions while protecting the lungs. Patients should be extubated in reverse Trendelenburg position. Postoperatively, continuous positive airway pressure helps prevent airway collapse and protocolized, early mobilization improves cognitive and respiratory function.

Indexed as

Continuous Positive Airway PressureAirway ObstructionAnesthesiaAnesthetics, InhalationHumansIncidenceIntensive Care UnitsIntraoperative CareLength of StayLung DiseasesNeuromuscular Blocking AgentsPostoperative ComplicationsPostoperative PeriodPractice Guidelines as TopicPreoperative CareRespiratory SystemAnesthetics, InhalationNeuromuscular Blocking Agents

Identifiers

PMID28323670
PMCPMC5434965
OpenAlexW2603000679

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.