Evidence map›Paper›PMID 28322850›Full record

ArticleThe Journal of allergy and clinical immunology2017

Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.

Eric J Allenspach, Laura S Finn, Mara H Rendi, Ahmet Eken, Akhilesh K Singh, Mohamed Oukka, Sean D Taylor, Matthew C Altman, Corinne L Fligner, Hans D Ochs and 2 more

Abstract readCase ReportsLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Intrauterine IPEX.Frontiers in pediatrics · 2020
    Review
  6. Memory CD4Nature immunology · 2019
    Article
  7. Article
  8. Review
  9. Unique aspects of the perinatal immune system.Nature reviews. Immunology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eric J AllenspachDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Laura S FinnDepartment of Laboratories, Seattle Children's Hospital, Seattle, Wash; Department of Pathology, University of Washington School of Medicine, Seattle, Wash.
Mara H RendiDepartment of Pathology, University of Washington School of Medicine, Seattle, Wash.
Ahmet EkenCenter for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Akhilesh K SinghCenter for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Mohamed OukkaCenter for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Sean D TaylorCenter for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Matthew C AltmanBenaroya Research Institute, Seattle, Wash; Department of Medicine, University of Washington School of Medicine, Seattle, Wash.
Corinne L FlignerDepartment of Pathology, University of Washington School of Medicine, Seattle, Wash; Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, Wash.
Hans D OchsDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
David J RawlingsDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash.
Troy R TorgersonDepartment of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash. Electronic address: troy.torgerson@seattlechildrens.org.

Funding

RESEARCH TRAINING IN RHEUMATOLOGYT32AR007108 · NIAMS · UNIVERSITY OF WASHINGTON · PI Shaun Jackson, Tomas M Mustelin · 1986 to 2026
$6.6M
Role of Dock8 in EAER21AI124735 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI OUKKA, MOHAMED · 2016 to 2017
$530k
FOXP3 Structure, Function and Regulatory Activity in T cellsK08AI063267 · NIAID · SEATTLE CHILDREN'S HOSPITAL · PI TORGERSON, TROY R · 2007 to 2009
$407k
NIAID NIH HHS K08 AI063267NIAID NIH HHS L40 AI057608NIAID NIH HHS R21 AI124735NIAMS NIH HHS T32 AR007108
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AutoimmunityAnimalsBiomarkersDisease Models, AnimalFetal DevelopmentHumansImmunohistochemistryImmunologic Deficiency SyndromesInfant, NewbornMiceMice, TransgenicOrgan SpecificityT-Lymphocytes, RegulatoryBiomarkers

Identifiers

PMID28322850
PMCPMC8941979

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.