Evidence map›Paper›PMID 28322314›Full record

ArticleScientific reports2017

The prognostic value of N-terminal proB-type natriuretic peptide in patients with acute respiratory distress syndrome.

Chih-Cheng Lai, Mei-I Sung, Chung-Han Ho, Hsiao-Hua Liu, Chin-Ming Chen, Shyh-Ren Chiang, Chien-Ming Chao, Wei-Lun Liu, Shu-Chen Hsing, Kuo-Chen Cheng

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chih-Cheng LaiDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Taiwan.
Mei-I SungDepartments of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Chung-Han HoDepartments of Medical Research, Chi Mei Medical Center, Tainan, Taiwan.
Hsiao-Hua LiuDepartments of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Chin-Ming ChenChia Nan University of Pharmacy &Science, Tainan, Taiwan.
Shyh-Ren ChiangDepartments of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Chien-Ming ChaoDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Taiwan.
Wei-Lun LiuDepartment of Intensive Care Medicine, Chi Mei Medical Center, Liouying, Taiwan.
Shu-Chen HsingDepartments of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Kuo-Chen ChengDepartments of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Chi Mei Medical Center · TWChia Nan University of Pharmacy and Science · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated whether N-terminal proB-type natriuretic peptide (NT-proBNP) predicts the prognosis of patients with acute respiratory distress syndrome (ARDS). Between December 1, 2012, and May 31, 2015, this observational study recruited patients admitted to our tertiary medical center who met the Berlin criteria for ARDS and who had their NT-proBNP measured. The main outcome was 28-day mortality. We enrolled 61 patients who met the Berlin criteria for ARDS: 7 were classified as mild, 29 as moderate, and 25 as severe. The median APACHE II scores were 23 (interquartile range [IQR], 18-28), and SOFA scores were 11 (IQR, 8-13). The median lung injury score was 3.0 (IQR, 2.50-3.25), and the median level of NT-proBNP was 2011 pg/ml (IQR, 579-7216). Thirty-four patients died during this study, and the 28-day mortality rate was 55.7%. Patients who die were older and had significantly (all p < 0.05) higher APACHE II scores and NT-proBNP levels than did patients who survived. Multivariate analysis identified age (HR: 1.546, 95% CI: 1.174-2.035, p = 0.0019) and NT-proBNP (HR: 1.009, 95% CI: 1.004-1.013, p = 0.0001) as significant risk factors of death. NT-proBNP was associated with poor outcomes for patients with ARDS, and its level predicted mortality.

Indexed as

AgedDemographyFemaleHumansMaleMiddle AgedNatriuretic Peptide, BrainPeptide FragmentsPrognosisRespiratory Distress SyndromeROC CurveSurvival AnalysisTreatment OutcomeNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)

Identifiers

PMID28322314
PMCPMC5359608
OpenAlexW2601850092

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.