Evidence map›Paper›PMID 28322189›Full record

ArticleeLife2017

Javier Periz, Jamie Whitelaw, Clare Harding, Simon Gras, Mario Igor Del Rosario Minina, Fernanda Latorre-Barragan, Leandro Lemgruber, Madita Alice Reimer, Robert Insall, Aoife Heaslip and 1 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.

0numbers the graph read from it
0cells of the map it votes in
72citing papers in PubMed
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

72 citing papers in PubMed, 125 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Molecular features of Myosin F adapted for driving actin flows inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Review
  10. Nanobodies in animal infectious disease control: diagnosis and therapy.Frontiers in cellular and infection microbiology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Architecture of theProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Detailing organelle division and segregation inbioRxiv : the preprint server for biology · 2024
    Article
  19. Myosin F controls actin organization and dynamics inMolecular biology of the cell · 2024
    Article
  20. Article

12 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Javier PerizWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Jamie WhitelawWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Clare HardingWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Simon GrasWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Mario Igor Del Rosario MininaWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Fernanda Latorre-BarraganWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Leandro LemgruberWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Madita Alice ReimerWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.
Robert InsallCancer Research United Kingdom Beatson Institute, Bearsden, United Kingdom.
Aoife HeaslipDepartment of Molecular Physiology and Biophysics, University of Vermont, Burlington, United States.
Markus MeissnerWellcome Centre for Molecular Parasitology, Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom.ORCID 0000-0002-4816-5221
Wellcome Centre for Molecular Parasitology · GBCancer Research UK Scotland Institute · GBUniversity of Vermont · US

Funding

Molecular mechanisms of dense granule trafficking in Toxoplasma gondiiR21AI121885 · NIAID · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI HEASLIP, AOIFE · 2016 to 2017
$431k
Cancer Research UK 15672Cancer Research UK 20017European Research Council 309255NIAID NIH HHS R21 AI121885Wellcome Trust
6 · The paper itself

Abstract

Apicomplexan actin is important during the parasite's life cycle. Its polymerization kinetics are unusual, permitting only short, unstable F-actin filaments. It has not been possible to study actin in vivo and so its physiological roles have remained obscure, leading to models distinct from conventional actin behaviour. Here a modified version of the commercially available actin-chromobody was tested as a novel tool for visualising F-actin dynamics in

Indexed as

ActinsStaining and LabelingToxoplasmaActinsactinApicomplexacell biologyinfectious diseasemicrobiologynanobodiesreplicationToxoplasma

Identifiers

PMID28322189
PMCPMC5375643
OpenAlexW2597789563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.