Evidence map›Paper›PMID 28322105›Full record

ArticleThe Journal of international medical research2016

Clinical features and biological markers of lung cancer-associated stroke.

Xingrui Xie, Li Chen, Jinsheng Zeng, Chao Qin, Daobin Cheng, Xinxian Wei, Zhijian Liang

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

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  8. Carbohydrate antigen 19-9 - tumor marker: Past, present, and future.World journal of gastrointestinal surgery · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Xingrui Xie1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Li Chen1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Jinsheng Zeng2 Department of Neurology, the First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Chao Qin1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Daobin Cheng1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Xinxian Wei1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Zhijian Liang1 Department of Neurology, the First Affiliated Hospital of Guangxi Medical University, Nanning, China.
First Affiliated Hospital of GuangXi Medical University · CNGuangxi Medical University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective To identify the unique clinical features and biological markers of lung cancer-associated stroke. Methods We recruited 102 patients with lung cancer plus stroke, 102 with lung cancer, and 102 with stroke. Detailed information was analysed and compared among groups. Results The groups were age-matched. Patients with lung cancer plus stroke showed multiple lesions involving multiple cerebral artery territories on magnetic resonance imaging, compared with stroke-alone patients. These patients also had a poorer modified Rankin Scale score at 30 days, and high mortality (18.6%). Patients with lung cancer plus stroke had a higher incidence of metastasis, and higher blood levels of D-dimer, CA125 and CA199 compared with patients with lung cancer alone. Multivariate logistic regression analysis showed that levels of D-dimer, CA125 and CA199 were independently related to lung cancer-associated stroke. Conclusion Elevated plasma D-dimer, CA125 and CA199 may be independent risk factors for and biomarkers of lung cancer-associated stroke.

Indexed as

AdultBiomarkersCA-125 AntigenCA-19-9 AntigenCerebral ArteriesDiffusion Magnetic Resonance ImagingFemaleFibrin Fibrinogen Degradation ProductsHumansLogistic ModelsLung NeoplasmsMagnetic Resonance AngiographyMaleMiddle AgedMultivariate AnalysisPrognosisBiomarkersCA-125 AntigenCA-19-9 AntigenFibrin Fibrinogen Degradation Productsfibrin fragment DBiological markerclinical presentationlung cancerpathogenesisrisk factorsstroke

Identifiers

PMID28322105
PMCPMC5536770
OpenAlexW2551139104

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.