Evidence map›Paper›PMID 28321897›Full record

ArticleBritish journal of clinical pharmacology2017

Statistical reporting of clinical pharmacology research.

Arne Ring, Robert Schall, Yoon K Loke, Simon Day

Abstract readEditorial
In one paragraph

Article in British journal of clinical pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Statistical reporting of clinical pharmacology research.British journal of clinical pharmacology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Arne RingUniversity of the Free State, Bloemfontein, South Africa.ORCID 0000-0002-4324-5820
Robert SchallUniversity of the Free State, Bloemfontein, South Africa.ORCID 0000-0002-4145-3685
Yoon K LokeNorwich Medical School, University of East Anglia, UK.ORCID 0000-0001-9109-2307
Simon DayClinical Trials Consulting & Training Limited, Buckingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research in clinical pharmacology covers a wide range of experiments, trials and investigations: clinical trials, systematic reviews and meta-analyses of drug usage after market approval, the investigation of pharmacokinetic-pharmacodynamic relationships, the search for mechanisms of action or for potential signals for efficacy and safety using biomarkers. Often these investigations are exploratory in nature, which has implications for the way the data should be analysed and presented. Here we summarize some of the statistical issues that are of particular importance in clinical pharmacology research.

Indexed as

Data Interpretation, StatisticalHumansModels, StatisticalPharmacology, ClinicalResearchSample Sizeclinical pharmacologyconfirmatory statisticsexploratory statisticsmeta-analysesrandomized clinical trials

Identifiers

PMID28321897
PMCPMC5427231

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.