ArticleRheumatology and therapy2017
Depression Risk in Patients with Rheumatoid Arthritis in the United Kingdom.
Article in Rheumatology and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Dissociation Between Functional Performance and Structural Joint Damage Following Sertraline Treatment in Collagen-Induced Arthritis.International journal of molecular sciences · 2026Article
- A Cross-Sectional Study of Depression in Rheumatoid Arthritis Patients at a Tertiary Care Center.Journal of pharmacy & bioallied sciences · 2025Article
- A qualitative survey on factors affecting depression and anxiety in patients with rheumatoid arthritis: a cross-sectional study in Syria.Scientific reports · 2024Article
- An exploratory study of brain temperature and choline abnormalities in temporal lobe epilepsy patients with depressive symptoms.Epilepsia open · 2023Article
- The frequency and factors affecting anxiety and depression in patients with rheumatoid arthritis.Reumatologia · 2023Article
- Association between chronic diseases and depression in the middle-aged and older adult Chinese population-a seven-year follow-up study based on CHARLS.Frontiers in public health · 2023Article
- The prevalence and correlation of depression and anxiety with disease activity in rheumatoid arthritis.Reumatologia · 2023Article
- The burden of rheumatoid arthritis in the Middle East and North Africa region, 1990-2019.Scientific reports · 2022Article
- Flavored Food Additives on the Leaves of Piper betle L.: A Human Health Perspective.Applied biochemistry and biotechnology · 2022Review
- Fecal microbiota transplantation from patients with rheumatoid arthritis causes depression-like behaviors in mice through abnormal T cells activation.Translational psychiatry · 2022Article
- Identification of key candidate genes and biological pathways in the synovial tissue of patients with rheumatoid arthritis.Experimental and therapeutic medicine · 2022Article
- Flare-up of cytokines in rheumatoid arthritis and their role in triggering depression: Shared common function and their possible applications in treatment (Review).Biomedical reports · 2021Review
- High Prevalence of Depressive Symptoms Among Ugandan Patients with Rheumatoid Arthritis.Open access rheumatology : research and reviews · 2021Article
- Electroacupuncture Relieves LPS-Induced Depression-Like Behaviour in Rats Through IDO-Mediated Tryptophan-Degrading Pathway.Neuropsychiatric disease and treatment · 2020Article
- Novel neuroimmunologic therapeutics in depression: A clinical perspective on what we know so far.Brain, behavior, and immunity · 2020Review
- Tumor Necrosis Factor Inhibitor Therapy and the Risk for Depression Among Working-Age Adults with Rheumatoid Arthritis.American health & drug benefits · 2019Article
- Depression as a risk factor for the development of rheumatoid arthritis: a population-based cohort study.RMD open · 2018Article
- Identification and Treatment Optimization of Comorbid Depression in Rheumatoid Arthritis.Rheumatology and therapy · 2017Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRheumatoid arthritis (RA) is one of the most common chronic inflammatory diseases. The goal of this study was to analyze the risk of depression in patients diagnosed with RA and treated by general practitioners in the UK.
methodsThe present study included patients first diagnosed with RA between 2000 and 2014 (index date). Individuals were excluded if they had also been diagnosed with depression or if they had received therapy for depression at or prior to the index date. The primary outcome measure was the rate of patients with depression (ICD 10: F32, 33) within 5 years of the RA diagnosis. Demographic data included gender and age. Furthermore, a revised version of the Charlson comorbidity index was used as a generic marker of comorbidity.
resultsA total of 4187 patients were included in the study. After 5 years of follow-up, 23.7% of men and 36.5% of women had developed depression (log rank p value <0.001). Women were more likely to develop depression than men (HR 1.61, 95% CI 1.42-1.84). Age and Charlson comorbidity score had no significant impact on the risk of being diagnosed with this psychiatric disorder.
conclusionAround 30% of RA patients developed depression within 5 years of the RA diagnosis. The depression risk was higher in women than in men. The current findings also indicate that improved detection and treatment of patients with both RA and depression are important.
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