ArticleAnnals of intensive care2017
Acute hyperventilation increases the central venous-to-arterial PCO
Article in Annals of intensive care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Renal Veno-Arterial Carbon Dioxide Gap Fails to Detect Renal Medulla Microcirculatory Changes in a Large Animal Model of Sepsis-Associated Acute Kidney Injury.Shock (Augusta, Ga.) · 2026Article
- Use of COAnnals of intensive care · 2025Review
- Association of the central venousFrontiers in pediatrics · 2025Article
- The Evolution of Central Venous-to-arterial Carbon Dioxide Difference (PCOIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2024Article
- Venous Minus Arterial Carbon Dioxide Gradients in the Monitoring of Tissue Perfusion and Oxygenation: A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
- Endothelial Function and Hypoxic-Hyperoxic Preconditioning in Coronary Surgery with a Cardiopulmonary Bypass: Randomized Clinical Trial.Biomedicines · 2023Article
- Pathophysiology and clinical implications of the veno-arterial PCOCritical care (London, England) · 2021Review
- Does measuring veno-arterial carbon dioxide difference compare to predicting a hockey game's final score?Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2021Article
- ΔPCOFrontiers in cardiovascular medicine · 2021Article
- Effects of respiratory rate on venous-to-arterial COEuropean journal of medical research · 2020Article
- Interpretation of venous-to-arterial carbon dioxide difference in the resuscitation of septic shock patients.Journal of thoracic disease · 2019Review
- Venous-to-arterial pCOJournal of thoracic disease · 2019Review
- How can COJournal of thoracic disease · 2019Review
- Shedding light on venoarterial PCOAnnals of intensive care · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTo evaluate the effects of acute hyperventilation on the central venous-to-arterial carbon dioxide tension difference (∆PCO
methodsEighteen mechanically ventilated septic shock patients were prospectively included in the study. We measured cardiac index (CI), ∆PCO
resultsArterial pH increased significantly (from 7.35 ± 0.07 to 7.42 ± 0.09, p < 0.001) and arterial carbon dioxide tension decreased significantly (from 44.5 [41-48] to 34 [30-38] mmHg, p < 0.001) when respiratory rate was increased. A statistically significant increase in VO
conclusionsAcute hyperventilation provoked a significant increase in ∆PCO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.