Evidence map›Paper›PMID 28321711›Full record

ReviewJournal of thrombosis and thrombolysis2017

Heparin induced thrombocytopenia with mechanical circulatory support devices: review of the literature and management considerations.

Jonathan Bain, Alexander H Flannery, Jeremy Flynn, William Dager

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of thrombosis and thrombolysis, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jonathan BainDepartment of Pharmacy Services, TriStar Centennial Medical Center, Nashville, TN, USA. jonabain@gmail.com.ORCID http://orcid.org/0000-0002-1310-3901
Alexander H FlanneryDepartment of Pharmacy Services, University of Kentucky HealthCare, Lexington, KY, USA.
Jeremy FlynnDepartment of Pharmacy Services, University of Kentucky HealthCare, Lexington, KY, USA.
William DagerUniversity of California-Davis Health System, Sacramento, CA, USA.
University of Kentucky HealthCare · USAmerican Association of Colleges of Pharmacy · USUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whether for temporary or long term use, mechanical circulatory support (MCS) has seen increased utilization and interest over the past several years. Even though these devices innately cause thrombocytopenia, co-administration of heparin anticoagulation carries the risk for heparin-induced thrombocytopenia (HIT). This poses challenges for practitioners as very few studies provide guidance for the management of this condition, particularly in this population. This has led to a wide spectrum of treatment protocols within current practice. This review was developed to bring together available literature on the management of HIT in patients with MCS along with practical experience and clinical opinion in order to help guide the management of these patients.

Indexed as

Extracorporeal CirculationHeparinHumansRisk FactorsThrombocytopeniaHeparinDirect thrombin inhibitorsECLSHeparin induced thrombocytopeniaHITMCSMechanical circulatory support

Identifiers

PMID28321711
OpenAlexW2603579485

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.