ArticleEnvironmental science and pollution research international2017
Association between level of urinary trace heavy metals and obesity among children aged 6-19 years: NHANES 1999-2011.
Article in Environmental science and pollution research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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43 citing papers in PubMed, 110 citations in OpenAlex.
- Exposure to metals and morbidity at eight years follow-up in women of childbearing age.Scientific reports · 2021Trial
- Associations of blood and urinary heavy metals with obesity risk among children: NHANES 2015-2020.Pediatric research · 2026Article
- Associations of Urinary Lead, Cadmium, and Arsenic Exposure with Obesity-Related Indicators Among School-Aged Children: A Longitudinal Study.Biological trace element research · 2026Article
- Antimony: a cryptic metabolism disruptor ubiquitous in food contact materials.Journal of the Endocrine Society · 2026Review
- Combination and Interaction of Seven Trace Elements and the Risk of Protein-Energy Malnutrition in School-Aged Children in Shenzhen, China.Biological trace element research · 2026Article
- Association between multiple urinary metals and visceral obesity: a large cross-sectional study in South China.European journal of medical research · 2026Article
- Early Life Exposure To Multiple Metals, Nutrition, and Growth in Children - A Scoping Review.Current environmental health reports · 2025Article
- Association of urinary perchlorate, nitrate, and thiocyanate concentrations with pulmonary function in children aged 6-19 years.BMC public health · 2025Article
- As, Cd, Hg, and Pb Biological Concentrations and Anthropometry in Slovak Adolescents.Biological trace element research · 2025Article
- Associations between metal exposure and metabolic syndrome: exploring the mediating role of biological ageing among US adults.Diabetology & metabolic syndrome · 2025Article
- Association between metal implants and urinary chromium levels in US adults: a cross-sectional study from NHANES.Scientific reports · 2024Article
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- The association between heavy metal exposure and obesity: A systematic review and meta-analysis.Journal of diabetes and metabolic disorders · 2024Review
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- Association between Heavy Metals, Metalloids and Metabolic Syndrome: New Insights and Approaches.Toxics · 2023Review
- Metal Homeostasis and Exposure in Distinct Phenotypic Subtypes of Insulin Resistance among Children with Obesity.Nutrients · 2023Article
- Environmental exposure to uranium in a population living in close proximity to gold mine tailings in South Africa.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023Article
- Accumulation of blood chromium and cobalt in the participants with metal objects: findings from the 2015 to 2018 National Health and Nutrition Examination Survey (NHANES).BMC geriatrics · 2023Article
- Article
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Global prevalence of obesity has been increasing dramatically in all ages. Although traditional causes for obesity development have been studied widely, it is unclear whether environmental exposure of substances such as trace heavy metals affects obesity development among children and adolescents so far. Data from the National Health and Nutrition Examination Survey (1999-2011) were retrieved, and 6602 US children were analyzed in this study. Urinary level of nine trace heavy metals, including barium, cadmium, cobalt, cesium, molybdenum, lead, antimony, thallium, and tungsten, was analyzed for their association with the prevalence of obesity among children aged 6-19 years. Multiple logistic regression was performed to assess the associations adjusted for age, race/ethnicity, gender, urinary creatinine, PIR, serum cotinine, and television, video game, and computer usage. A remarkable association was found between barium exposure (OR 1.43; 95% CI 1.09-1.88; P < 0.001) and obesity in children aged 6-19 years. Negative association was observed between cadmium (OR 0.46; 95% CI 0.33-0.64; P < 0.001), cobalt (OR 0.56; 95% CI: 0.41-0.76; P < 0.001), and lead (OR 0.57; 95% CI 0.41-0.78; P = 0.018), and obesity. All the negative associations were stronger in the 6-12 years group than in the 13-19 years group. The present study demonstrated that barium might increase the occurrence of obesity, but cadmium, cobalt, and lead caused weight loss among children. The results imply that trace heavy metals may represent critical risk factors for the development of obesity, especially in the area that the state of metal contamination is serious.
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