Trial reportEuropean journal of applied physiology2017
The time course of short-term hypertrophy in the absence of eccentric muscle damage.
Trial report in European journal of applied physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05504616 (Physical Activity in Axial Spondyloarthritis), which is not on this map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physical Activity in Axial Spondyloarthritis: Development and Implementation of an Evidence-Based Health Technology Approach to Improve Adherence to Recommended Guidelines
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Determining the Sites of Neural Adaptations to Resistance Training: A Systematic Review and Meta-analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Effect of ischemic preconditioning on microvascular post-occlusive hyperemic reactions and quadriceps morphology in MMA: a randomized clinical trial.European journal of applied physiology · 2026Trial
- Influence of Structured Medium- and Long-Chain Triglycerides on Muscular Recovery Following Damaging Resistance Exercise.Nutrients · 2025Trial
- Cross-education attenuates muscle weakness and facilitates strength recovery after orthopedic immobilization in females: A pilot study.Physiological reports · 2025Trial
- Flywheel resistance training promotes unique muscle architectural and performance-related adaptations in young adults.European journal of sport science · 2024Trial
- A Retrospective Analysis to Determine Whether Training-Induced Changes in Muscle Thickness Mediate Changes in Muscle Strength.Sports medicine (Auckland, N.Z.) · 2021Trial
- Comparison of Strength Training Interventions on Functional Performance in Frail Nursing Home Residents.Healthcare (Basel, Switzerland) · 2026Article
- Early Phase Adaptations in Strength, Muscle Size, and Co-activation Following Resistance Training in Untrained Women.International journal of exercise science · 2026Article
- Muscle quality responses to short-term resistance training volume in older adults: an exploratory clinical trial.Frontiers in aging · 2025Article
- Task-specific resistance training adaptations in older adults: comparing traditional and functional exercise interventions.Frontiers in aging · 2024Article
- Exploring the Relationship between Ultrasonographic Measures of the Quadriceps and Knee Extensor Muscle Fitness in Endurance-Trained Individuals.Translational sports medicine · 2024Article
- Skeletal Muscle Ultrasonography and Muscle Fitness Relationships: Effects of Scanning Plane and Echogenicity Correction.Muscles (Basel, Switzerland) · 2023Article
- Blood Flow Restriction Attenuates Muscle Damage in Resistance Exercise Performed Until Concentric Muscle Failure.International journal of exercise science · 2023Article
- Myofibrillar protein synthesis rates are increased in chronically exercised skeletal muscle despite decreased anabolic signaling.Scientific reports · 2022Article
- The time course of different neuromuscular adaptations to short-term downhill running training and their specific relationships with strength gains.European journal of applied physiology · 2022Article
- Multi-scale mechanobiological model for skeletal muscle hypertrophy.Frontiers in physiology · 2022Article
- The Influence of Sonographer Experience on Skeletal Muscle Image Acquisition and Analysis.Journal of functional morphology and kinesiology · 2021Article
- Why exercise builds muscles: titin mechanosensing controls skeletal muscle growth under load.Biophysical journal · 2021Article
- Does skeletal muscle morphology or functional performance better explain variance in fast gait speed in older adults?Aging clinical and experimental research · 2021Article
- Echo intensity as an indicator of skeletal muscle quality: applications, methodology, and future directions.European journal of applied physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIt has been proposed that the increase in skeletal muscle mass observed during the initial weeks of initiating a resistance training program is concomitant with eccentric muscle damage and edema. PURPOSE: We examined the time course of muscle hypertrophy during 4 weeks of concentric-only resistance training.
methodsThirteen untrained men performed unilateral concentric-only dumbbell curls and shoulder presses twice per week for 4 weeks. Sets of 8-12 repetitions were performed to failure, and training loads were increased during each session. Subjects consumed 500 ml of whole milk during training. Assessments of soreness, lean mass, echo intensity, muscle thickness, relaxed and flexed arm circumference, and isokinetic strength were performed every 72 or 96 h.
resultsSoreness, echo intensity, relaxed circumference, and peak torque data did not significantly change. Significant increases in lean mass, muscle thickness, and flexed circumference were observed within seven training sessions. Lean mass was elevated at tests #7 (+109.3 g, p = .002) and #8 (+116.1 g, p = .035), with eight different subjects showing changes above the minimal difference of 139.1 g. Muscle thickness was elevated at tests #6 (+0.23 cm, p = .004), #7 (+0.31 cm, p < .001), and #8 (+0.27 cm, p < .001), with ten subjects exceeding the minimal difference of 0.24 cm. There were no changes for the control arm.
conclusionIn individuals beginning a resistance training program, small but detectable increases in hypertrophy may occur in the absence of eccentric muscle damage within seven training sessions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.