Evidence map›Paper›PMID 28321573›Full record

Trial reportHeart and vessels2017

A longer total duration of rapid ventricular pacing does not increase the risk of postprocedural myocardial injury in patients who undergo transcatheter aortic valve implantation.

Kenta Okitsu, Takeshi Iritakenishi, Tatsuyuki Imada, Mitsuo Iwasaki, Sho Carl Shibata, Yuji Fujino

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Heart and vessels, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kenta OkitsuDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan. kokitsu@anes.med.osaka-u.ac.jp.ORCID http://orcid.org/0000-0003-0655-826X
Takeshi IritakenishiDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.
Tatsuyuki ImadaDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.
Mitsuo IwasakiDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.
Sho Carl ShibataDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.
Yuji FujinoDepartment of Anesthesiology and Intensive Care Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka, Japan.
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid ventricular pacing (RVP) is used during transcatheter aortic valve implantation (TAVI). RVP disturbs myocardial oxygen balance, and when prolonged, it may cause procedure-related myocardial injury (PMI). This study investigated whether a longer duration of RVP increased the occurrence of PMI or worsened long-term mortality after TAVI. We retrospectively analyzed data from 188 patients who underwent TAVI in our institute from January 2013 to July 2015. Myocardial injury was represented by the peak value of creatine kinase-myocardial band (CK-MB) within 72 h after the procedure; an increase greater than 5 times the upper reference limit was regarded as PMI. There was no difference in RVP time (RVPT) between patients with and without PMI (median [range]: 57 [9-189] s vs. 54 [0-159] s, p = 0.9). A higher peak CK-MB was significantly correlated with the apical approach for the procedure (p < 0.001) but not with total RVPT (p = 0.22). A subanalysis of 133 patients whose troponin I was tested within 72 h postprocedurally showed no correlation between the peak value and RVPT (p = 0.40). Shortening RVPT did not result in myocardial protection; thus, RVPT during TAVI should be sufficient to optimize valve placement.

Indexed as

Risk AssessmentAgedAged, 80 and overAortic Valve StenosisCardiac Pacing, ArtificialFemaleFollow-Up StudiesHumansIncidenceIntraoperative CareJapanMaleMiddle AgedMyocardial Reperfusion InjuryPostoperative ComplicationsRetrospective StudiesMyocardial protectionRapid ventricular pacingTAVI

Identifiers

PMID28321573
OpenAlexW2599336505

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.