SynthesisBioMed research international2017
Could the Topping-Off Technique Be the Preventive Strategy against Adjacent Segment Disease after Pedicle Screw-Based Fusion in Lumbar Degenerative Diseases? A Systematic Review.
Synthesis in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Dynamic Stabilization Adjacent to Fusion versus Posterior Lumbar Interbody Fusion for the Treatment of Lumbar Degenerative Disease: A Meta-Analysis.BioMed research international · 2020Pooled it
- Topping-Off Technology versus Posterior Lumbar Interbody Fusion in the Treatment of Lumbar Disc Herniation: A Meta-Analysis.BioMed research international · 2020Pooled it
- Pooled it
- Low-Profile Posterior Lumbar Fusion Combined With Proximal Interlaminar Coflex Dynamic Fixation for Lumbar Degenerative Diseases: A Comparative Study.Orthopaedic surgery · 2026Article
- Biomechanical analysis of the interlaminar dynamic stabilization system (IntraSPINE) in unilateral biportal endoscopic discectomy for huge lumbar disc herniation: a finite element study.BMC musculoskeletal disorders · 2026Article
- Article
- The influence of the interfacing angle between the pedicle screw and support rods on the clinical outcomes after posterior lumbar-sacral topping-off surgery: A retrospective clinical study.Journal of orthopaedic surgery and research · 2025Observational
- Risk factors and treatment strategies for adjacent segment disease following spinal fusion (Review).Molecular medicine reports · 2025Review
- Percutaneous Full Endoscopic Lumbar Discectomy for Symptomatic Adjacent Segment Disease after Lumbar Fusion in Elderly Patients.Orthopaedic surgery · 2023Article
- The effect of interlaminar Coflex stabilization in the topping-off procedure on local and global spinal sagittal alignment.BMC musculoskeletal disorders · 2023Article
- Dynamic Rod Constructs as the Preventive Strategy against Adjacent Segment Disease in Degenerative Lumbar Spinal Disorders: A Retrospective Comparative Cohort Study.The archives of bone and joint surgery · 2023Article
- Comparison of long-term outcomes of spinal fusion surgeries supplemented with "topping-off" implants in lumbar degenerative diseases: A systematic review and network meta-analysis.North American Spine Society journal · 2022Review
- Dynamic Fixation Techniques for the Prevention of Adjacent Segment Disease: A Retrospective Controlled Study.Asian spine journal · 2022Article
- Hybrid surgery with PEEK rods for lumbar degenerative diseases: a 2-year follow-up study.BMC musculoskeletal disorders · 2022Article
- Biomechanical investigation of topping-off technique using an interspinous process device following lumbar interbody fusion under vibration loading.Medical & biological engineering & computing · 2021Article
- Biomechanical analysis of lumbar interbody fusion supplemented with various posterior stabilization systems.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Article
- Risk of adjacent segment disease after 'topping-off' multi-level lumbar fusions with posterior dynamic stabilisers: an observational cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2021Observational
- Mobility-Preserving Surgery for Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations.World neurosurgery: X · 2020Article
- Topping-off surgery vs posterior lumbar interbody fusion for degenerative lumbar disease: a finite element analysis.Journal of orthopaedic surgery and research · 2019Article
- Managing lumbar adjacent segment disease: A description of minimally invasive techniques and algorithm.Journal of craniovertebral junction & spineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The "topping-off" technique is a new concept applying dynamic or less rigid fixation such as hybrid stabilization device (HSD) or interspinous process device (IPD) for the purpose of avoiding adjacent segment disease (ASD) proximal to the fusion construct. A systematic review of the literature was performed on the effect of topping-off techniques to prevent or decrease the occurrence of ASD after lumbar fusion surgery. We searched through major online databases, PubMed and MEDLINE, using key words related to "topping-off" technique. We reviewed the surgical results of "topping-off" techniques with either HSD or IPD, including the incidence of ASD at two proximal adjacent levels (index and supra-adjacent level) as compared to the fusion alone group. The results showed that the fusion alone group had statistically higher incidence of radiographic (52.6%) and symptomatic (11.6%) ASD at the index level as well as higher incidence (8.1%) of revision surgery. Besides, the HSD (10.5%) and fusion groups (24.7%) had statistically higher incidences of radiographic ASD at supra-adjacent level than the IPD (1%). The findings suggest that the "topping-off" technique may potentially decrease the occurrence of ASD at the proximal motion segments. However, higher quality prospective randomized trials are required prior to wide clinical application.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.