Evidence map›Paper›PMID 28321292›Full record

ArticleClinical and translational allergy2017

Low percentage of clinically relevant pistachio nut and mango co-sensitisation in cashew nut sensitised children.

J P M van der Valk, R El Bouche, R Gerth van Wijk, H de Groot, H J Wichers, A E J Dubois, N W de Jong

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and translational allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04801823 (Can Early Introduction of Tree Nuts Prevent Tree Nut Allergy in Infants at High Risk of Tree Nut Allergy), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04801823 phase3completednot on this mapstarted 2021, after this paper: background citation

Can Early Introduction of Tree Nuts Prevent Tree Nut Allergy in Infants at High Risk of Tree Nut Allergy: The TreEat Study: a Randomised, Open-label Controlled Trial

TypeinterventionalSponsorMurdoch Childrens Research InstituteRan2021 to 2025Enrolled212ConditionsFood Allergy in Infants, Nut AllergyArmsHome introduction, Multi Nut oral food challenge
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 29 citations in OpenAlex.

  1. Tree nut allergy.Postepy dermatologii i alergologii · 2021
    Review
  2. Article
  3. Recent advances in the management of nut allergy.The World Allergy Organization journal · 2021
    Review
  4. Article
  5. Anaphylactic reaction in patient allergic to mango.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2018
    Article
  6. Current perspectives on tree nut allergy: a review.Journal of asthma and allergy · 2018
    Review
  7. IgE Cross-Reactivity of Cashew Nut Allergens.International archives of allergy and immunology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

J P M van der Valk *Department of Internal Medicine, Section of Allergology, Erasmus MC, Office Gk 323, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
R El Bouche *Department of Internal Medicine, Section of Allergology, Erasmus MC, Office Gk 323, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
R Gerth van WijkDepartment of Internal Medicine, Section of Allergology, Erasmus MC, Office Gk 323, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
H de GrootDepartment of Paediatric Allergology, Diaconessenhuis Voorburg, RdGG, Delft, The Netherlands.
H J WichersFood and Biobased Research, Wageningen University and Research Centre, Wageningen, The Netherlands.
A E J DuboisDepartment of Paediatric Pulmonology and Paediatric Allergology, University Medical Centre Groningen, GRIAC Research Institute, University of Groningen, Groningen, The Netherlands.
N W de JongDepartment of Internal Medicine, Section of Allergology, Erasmus MC, Office Gk 323, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.
Erasmus MC · NLErasmus University Rotterdam · NLDiakonessenhuis hospital · NLUniversity of Groningen · NLWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCashew nut, pistachio nut and mango belong to the

methodsChildren were recruited from the study: 'Improvement of Diagnostic mEthods for ALlergy assessment (IDEAL trial number NTR3572). Inclusion criterion for the IDEAL study was sensitization to cashew nut as demonstrated by either SPT or sIgE, and a clinical history of reactions to cashew nuts or no previous (known) exposure. Sensitized children who were tolerant to cashew nuts were excluded. Inclusion criterion for this IDEAL follow-up study was co-sensitization to pistachio nut, regardless the result of the DBPCFC with cashew nut. In this follow-up study a double-blind placebo-controlled food challenge with pistachio nut and an open food challenge with mango were performed.

resultsTwenty-nine children (mean age of 11.6 years, 62% male) were included. Pistachio nut sensitisation was clinically relevant in only 34% of cashew-sensitised children and only 31% of cashew challenge positive children. None of the children was challenge positive to mango.

conclusionAlthough co-sensitisation between cashew nut and pistachio nut was observed in 98%, pistachio nut sensitisation was only clinically relevant in 34% of the children. Therefore, a challenge test with pistachio nut is recommended in children with cashew nut and pistachio nut sensitisation.

Indexed as

Cashew nut allergyChildrenCo-sensitisationFood challenge testMango allergyPistachio nut allergy

Identifiers

PMID28321292
PMCPMC5357817
OpenAlexW2596035516

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.