Evidence map›Paper›PMID 28321257›Full record

ArticleInternational journal of cell biology2017

Class-Specific Histone Deacetylase Inhibitors Promote 11-Beta Hydroxysteroid Dehydrogenase Type 2 Expression in JEG-3 Cells.

Katie L Togher, Louise C Kenny, Gerard W O'Keeffe

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Katie L TogherDepartment of Obstetrics and Gynaecology, Cork University Maternity Hospital, University College Cork, Cork, Ireland; APC Microbiome Institute, Biosciences Institute, University College Cork, Cork, Ireland; INFANT Centre, Cork University Maternity Hospital, University College Cork, Cork, Ireland.
Louise C KennyDepartment of Obstetrics and Gynaecology, Cork University Maternity Hospital, University College Cork, Cork, Ireland; INFANT Centre, Cork University Maternity Hospital, University College Cork, Cork, Ireland.
Gerard W O'KeeffeAPC Microbiome Institute, Biosciences Institute, University College Cork, Cork, Ireland; INFANT Centre, Cork University Maternity Hospital, University College Cork, Cork, Ireland; Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland.ORCID 0000-0001-5149-0933
University College Cork · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to maternal cortisol plays a crucial role in fetal organogenesis. However, fetal overexposure to cortisol has been linked to a range of short- and long-term adverse outcomes. Normally, this is prevented by the expression of an enzyme in the placenta called 11-beta hydroxysteroid dehydrogenase type 2 (11

Identifiers

PMID28321257
PMCPMC5339487
OpenAlexW2590400289

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.