Evidence map›Paper›PMID 28321214›Full record

ArticleFrontiers in immunology2017

Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens.

Xin-Hai Chen, Shi-Rao Liu, Bo Peng, Dan Li, Zhi-Xue Cheng, Jia-Xin Zhu, Song Zhang, Yu-Ming Peng, Hui Li, Tian-Tuo Zhang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Upregulated Palmitoleate and Oleate Production inMolecules (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. The biological functions and metabolic pathways of valine in swine.Journal of animal science and biotechnology · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xin-Hai ChenCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Shi-Rao LiuCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Bo PengCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Dan LiCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Zhi-Xue ChengCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Jia-Xin ZhuThird Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.
Song ZhangCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Yu-Ming PengCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Hui LiCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Tian-Tuo ZhangThird Affiliated Hospital of Sun Yat-sen University , Guangzhou , China.
Xuan-Xian PengCenter for Proteomics, State Key Laboratory of Bio-Control, School of Life Sciences, Guangdong Province Key Laboratory for Pharmaceutical Functional Genes, Sun Yat-sen University , Guangzhou , China.
Sun Yat-sen University · CNThird Affiliated Hospital of Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The emergence of multidrug-resistant bacteria presents a severe threat to public health and causes extensive losses in livestock husbandry and aquaculture. Effective strategies to control such infections are in high demand. Enhancing host immunity is an ideal strategy with fewer side effects than antibiotics. To explore metabolite candidates, we applied a metabolomics approach to investigate the metabolic profiles of mice after

Indexed as

bacterial infectionsl-argininel-valinenitric oxidephagocytosis

Identifiers

PMID28321214
PMCPMC5337526
OpenAlexW2591978130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.